Wee1 Kinase: A Potential Target to Overcome Tumor Resistance to Therapy

Wee1 Kinase: A Potential Target to Overcome Tumor Resistance to Therapy

During the cell cycle, DNA suffers several lesions that need to be repaired prior to entry into mitosis to preserve genome integrity in daughter cells. Toward this aim, cells have developed complex enzymatic machinery, the so-called DNA damage response (DDR), which is able to repair DNA, temporarily...

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Bibliographic Details
Main Authors: Francesca Esposito, Raffaella Giuffrida, Gabriele Raciti, Caterina Puglisi, Stefano Forte
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
Wee1 kinase
cell cycle
tumor resistance
Online Access:https://www.mdpi.com/1422-0067/22/19/10689

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