A case of primary pulmonary leiomyosarcoma completely resected after neoadjuvant chemotherapy
Abstract Background Primary pulmonary leiomyosarcoma is a rare malignant tumor. We herein report a case of primary pulmonary leiomyosarcoma that was completely resected by surgery after neoadjuvant chemotherapy. Case presentation A 60-year-old man presented with cough. Chest computed tomography show...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2019-05-01
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| Series: | Surgical Case Reports |
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| Online Access: | http://link.springer.com/article/10.1186/s40792-019-0649-y |
| _version_ | 1818304667004698624 |
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| author | Kazuhisa Tanaka Takekazu Iwata Kai Nishii Yukiko Matsui Tsukasa Yonemoto Hidetada Kawana Makiko Itami Shigetoshi Yoshida Toshihiko Iizasa |
| author_facet | Kazuhisa Tanaka Takekazu Iwata Kai Nishii Yukiko Matsui Tsukasa Yonemoto Hidetada Kawana Makiko Itami Shigetoshi Yoshida Toshihiko Iizasa |
| author_sort | Kazuhisa Tanaka |
| collection | DOAJ |
| description | Abstract Background Primary pulmonary leiomyosarcoma is a rare malignant tumor. We herein report a case of primary pulmonary leiomyosarcoma that was completely resected by surgery after neoadjuvant chemotherapy. Case presentation A 60-year-old man presented with cough. Chest computed tomography showed an 11-cm mass in the right upper lobe of the lung that had invaded the superior vena cava. Endobronchial ultrasound-guided transbronchial needle aspiration revealed leiomyosarcoma of the lung. We considered complete resection of the tumor to be very difficult because of the tumor invasion into the right atrium inflow of the superior vena cava, so we performed chemotherapy using doxorubicin for five cycles. After chemotherapy, the tumor size decreased to 5.6 cm, and we performed right upper lobectomy with combined resection of the superior vena cava. The tumor was completely resected by surgery. The patient is alive without recurrence 17 months postoperatively. Conclusions We encountered a case of primary pulmonary leiomyosarcoma that was successfully treated by surgery after neoadjuvant chemotherapy. Doxorubicin monotherapy was effective in this case. Surgery combined with neoadjuvant chemotherapy should be considered for such cases, as a long-term survival can be achieved by complete resection of primary pulmonary leiomyosarcoma. |
| first_indexed | 2024-12-13T06:14:20Z |
| format | Article |
| id | doaj.art-4046307391bc4b34bde6eb43fa629516 |
| institution | Directory Open Access Journal |
| issn | 2198-7793 |
| language | English |
| last_indexed | 2024-12-13T06:14:20Z |
| publishDate | 2019-05-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj.art-4046307391bc4b34bde6eb43fa6295162022-12-21T23:57:00ZengSpringerOpenSurgical Case Reports2198-77932019-05-01511410.1186/s40792-019-0649-yA case of primary pulmonary leiomyosarcoma completely resected after neoadjuvant chemotherapyKazuhisa Tanaka0Takekazu Iwata1Kai Nishii2Yukiko Matsui3Tsukasa Yonemoto4Hidetada Kawana5Makiko Itami6Shigetoshi Yoshida7Toshihiko Iizasa8Division of Thoracic Surgery, Chiba Cancer CenterDivision of Thoracic Surgery, Chiba Cancer CenterDivision of Thoracic Surgery, Chiba Cancer CenterDivision of Thoracic Surgery, Chiba Cancer CenterDivision of Orthopedic Surgery, Chiba Cancer CenterDivision of Surgical Pathology, Chiba Cancer CenterDivision of Surgical Pathology, Chiba Cancer CenterDivision of Thoracic Surgery, Chiba Cancer CenterDivision of Thoracic Surgery, Chiba Cancer CenterAbstract Background Primary pulmonary leiomyosarcoma is a rare malignant tumor. We herein report a case of primary pulmonary leiomyosarcoma that was completely resected by surgery after neoadjuvant chemotherapy. Case presentation A 60-year-old man presented with cough. Chest computed tomography showed an 11-cm mass in the right upper lobe of the lung that had invaded the superior vena cava. Endobronchial ultrasound-guided transbronchial needle aspiration revealed leiomyosarcoma of the lung. We considered complete resection of the tumor to be very difficult because of the tumor invasion into the right atrium inflow of the superior vena cava, so we performed chemotherapy using doxorubicin for five cycles. After chemotherapy, the tumor size decreased to 5.6 cm, and we performed right upper lobectomy with combined resection of the superior vena cava. The tumor was completely resected by surgery. The patient is alive without recurrence 17 months postoperatively. Conclusions We encountered a case of primary pulmonary leiomyosarcoma that was successfully treated by surgery after neoadjuvant chemotherapy. Doxorubicin monotherapy was effective in this case. Surgery combined with neoadjuvant chemotherapy should be considered for such cases, as a long-term survival can be achieved by complete resection of primary pulmonary leiomyosarcoma.http://link.springer.com/article/10.1186/s40792-019-0649-yPrimary pulmonary leiomyosarcomaSurgeryNeoadjuvant chemotherapy |
| spellingShingle | Kazuhisa Tanaka Takekazu Iwata Kai Nishii Yukiko Matsui Tsukasa Yonemoto Hidetada Kawana Makiko Itami Shigetoshi Yoshida Toshihiko Iizasa A case of primary pulmonary leiomyosarcoma completely resected after neoadjuvant chemotherapy Surgical Case Reports Primary pulmonary leiomyosarcoma Surgery Neoadjuvant chemotherapy |
| title | A case of primary pulmonary leiomyosarcoma completely resected after neoadjuvant chemotherapy |
| title_full | A case of primary pulmonary leiomyosarcoma completely resected after neoadjuvant chemotherapy |
| title_fullStr | A case of primary pulmonary leiomyosarcoma completely resected after neoadjuvant chemotherapy |
| title_full_unstemmed | A case of primary pulmonary leiomyosarcoma completely resected after neoadjuvant chemotherapy |
| title_short | A case of primary pulmonary leiomyosarcoma completely resected after neoadjuvant chemotherapy |
| title_sort | case of primary pulmonary leiomyosarcoma completely resected after neoadjuvant chemotherapy |
| topic | Primary pulmonary leiomyosarcoma Surgery Neoadjuvant chemotherapy |
| url | http://link.springer.com/article/10.1186/s40792-019-0649-y |
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