Pharmacognostic study and development of quality control parameters for fruit, bark and leaf of Zanthoxylum armatum (Rutaceae)
Context: Zanthoxylum armatum (Rutaceae) fruit, bark and leaves are used for various conditions of ailments in traditional systems of medicine since ancient times. Aims: This study is designed to lay down the various pharmacognostic and phytochemical standards which will be helpful to ensure the pur...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Ancient Science of Life |
| Subjects: | |
| Online Access: | http://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2015;volume=34;issue=3;spage=147;epage=155;aulast=Alam |
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| author | Fiaz Alam Qazi Najam Us Saqib |
| author_facet | Fiaz Alam Qazi Najam Us Saqib |
| author_sort | Fiaz Alam |
| collection | DOAJ |
| description | Context: Zanthoxylum armatum (Rutaceae) fruit, bark and leaves are used for various conditions of ailments in traditional systems of medicine since ancient times.
Aims: This study is designed to lay down the various pharmacognostic and phytochemical standards which will be helpful to ensure the purity, safety, and efficacy of this medicinal plant.
Materials and Methods: Various methods including macroscopic, microscopic, physicochemical, and phytochemical methods were applied to determine the diagnostic features for the identification and standardization of intact and powdered drug of Z. armatum leaf, fruit, and bark.
Results: The shape, size, color, odor, surface characteristics were determined for the intact drug and powdered materials of leaf, bark and fruit of Z. armatum. Light and electron microscope images of cross-section of leaf and powdered microscopy revealed useful diagnostic features. Histochemical, phytochemical, physicochemical including fluorescence analysis of powdered drug proved useful to differentiate the powdered drug material. High performance liquid chromatography analysis showed the presence of important phytoconstituents such as gallic acid and rutin.
Conclusion: The data generated from this study would be of help in the authentication of various parts of Z. armatum, an important constituent of various herbal drug formulations. The qualitative and quantitative microscopic features would prove useful for laying down pharmacopoeial standards. Morphology as well as various pharmacognostic aspects of different parts of the plant were studied and have been described here along with phytochemical, physicochemical studies, which will help in authentication and quality control. |
| first_indexed | 2024-12-12T17:01:39Z |
| format | Article |
| id | doaj.art-4047a5695f9541b186bc9acd11fac9ae |
| institution | Directory Open Access Journal |
| issn | 0257-7941 |
| language | English |
| last_indexed | 2024-12-12T17:01:39Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Ancient Science of Life |
| spelling | doaj.art-4047a5695f9541b186bc9acd11fac9ae2022-12-22T00:18:07ZengWolters Kluwer Medknow PublicationsAncient Science of Life0257-79412015-01-0134314715510.4103/0257-7941.157159Pharmacognostic study and development of quality control parameters for fruit, bark and leaf of Zanthoxylum armatum (Rutaceae)Fiaz AlamQazi Najam Us SaqibContext: Zanthoxylum armatum (Rutaceae) fruit, bark and leaves are used for various conditions of ailments in traditional systems of medicine since ancient times. Aims: This study is designed to lay down the various pharmacognostic and phytochemical standards which will be helpful to ensure the purity, safety, and efficacy of this medicinal plant. Materials and Methods: Various methods including macroscopic, microscopic, physicochemical, and phytochemical methods were applied to determine the diagnostic features for the identification and standardization of intact and powdered drug of Z. armatum leaf, fruit, and bark. Results: The shape, size, color, odor, surface characteristics were determined for the intact drug and powdered materials of leaf, bark and fruit of Z. armatum. Light and electron microscope images of cross-section of leaf and powdered microscopy revealed useful diagnostic features. Histochemical, phytochemical, physicochemical including fluorescence analysis of powdered drug proved useful to differentiate the powdered drug material. High performance liquid chromatography analysis showed the presence of important phytoconstituents such as gallic acid and rutin. Conclusion: The data generated from this study would be of help in the authentication of various parts of Z. armatum, an important constituent of various herbal drug formulations. The qualitative and quantitative microscopic features would prove useful for laying down pharmacopoeial standards. Morphology as well as various pharmacognostic aspects of different parts of the plant were studied and have been described here along with phytochemical, physicochemical studies, which will help in authentication and quality control.http://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2015;volume=34;issue=3;spage=147;epage=155;aulast=AlamPharmacognosticphysicochemicalphytochemicalstandardizationZanthoxylum armatum |
| spellingShingle | Fiaz Alam Qazi Najam Us Saqib Pharmacognostic study and development of quality control parameters for fruit, bark and leaf of Zanthoxylum armatum (Rutaceae) Ancient Science of Life Pharmacognostic physicochemical phytochemical standardization Zanthoxylum armatum |
| title | Pharmacognostic study and development of quality control parameters for fruit, bark and leaf of Zanthoxylum armatum (Rutaceae) |
| title_full | Pharmacognostic study and development of quality control parameters for fruit, bark and leaf of Zanthoxylum armatum (Rutaceae) |
| title_fullStr | Pharmacognostic study and development of quality control parameters for fruit, bark and leaf of Zanthoxylum armatum (Rutaceae) |
| title_full_unstemmed | Pharmacognostic study and development of quality control parameters for fruit, bark and leaf of Zanthoxylum armatum (Rutaceae) |
| title_short | Pharmacognostic study and development of quality control parameters for fruit, bark and leaf of Zanthoxylum armatum (Rutaceae) |
| title_sort | pharmacognostic study and development of quality control parameters for fruit bark and leaf of zanthoxylum armatum rutaceae |
| topic | Pharmacognostic physicochemical phytochemical standardization Zanthoxylum armatum |
| url | http://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2015;volume=34;issue=3;spage=147;epage=155;aulast=Alam |
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