Upregulation of SNTB1 correlates with poor prognosis and promotes cell growth by negative regulating PKN2 in colorectal cancer

Upregulation of SNTB1 correlates with poor prognosis and promotes cell growth by negative regulating PKN2 in colorectal cancer

Abstract Background Colorectal cancer (CRC) is one of the most highly malignant tumors and has a complicated pathogenesis. A preliminary study identified syntrophin beta 1 (SNTB1) as a potential oncogene in CRC. However, the clinical significance, biological function, and underlying mechanisms of SN...

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Bibliographic Details
Main Authors: Liya Liu, Youqin Chen, Xiaoying Lin, Meizhu Wu, Jiapeng Li, Qiurong Xie, Thomas J. Sferra, Yuying Han, Huixin Liu, Liujing Cao, Mengying Yao, Jun Peng, Aling Shen
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Cancer Cell International
Subjects:
Colorectal cancer
Syntrophin beta 1
Growth
Overall survival
Protein kinase N2
Online Access:https://doi.org/10.1186/s12935-021-02246-7

Internet

https://doi.org/10.1186/s12935-021-02246-7

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