Changes in the Number and Morphology of Dendritic Spines in the Hippocampus and Prefrontal Cortex of the C58/J Mouse Model of Autism

Changes in the Number and Morphology of Dendritic Spines in the Hippocampus and Prefrontal Cortex of the C58/J Mouse Model of Autism

Autism spectrum disorder (ASD) has a broad range of neurobiological characteristics, including alterations in dendritic spines, where approximately 90% of excitatory synapses occur. Therefore, changes in their number or morphology would be related to atypical brain communication. The C58/J inbred mo...

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Bibliographic Details
Main Authors: Isabel Barón-Mendoza, Emely Maqueda-Martínez, Mónica Martínez-Marcial, Marisol De la Fuente-Granada, Margarita Gómez-Chavarin, Aliesha González-Arenas
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
autism
dendritic spines
structural plasticity
hippocampus
prefrontal cortex
C58/J
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.726501/full

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