Quantitative Analysis of the Specific Absorption Rate Dependence on the Magnetic Field Strength in Zn<sub>x</sub>Fe<sub>3−x</sub>O<sub>4</sub> Nanoparticles
Superparamagnetic Zn<sub>x</sub>Fe<sub>3−x</sub>O<sub>4</sub> magnetic nanoparticles (0 ≤ x < 0.5) with spherical shapes of 16 nm average diameter and different zinc doping level have been successfully synthesized by co-precipitation method. The homogeneous zin...
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MDPI AG
2020-10-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/21/20/7775 |
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| author | Mohamed Alae Ait Kerroum Cristian Iacovita Walid Baaziz Dris Ihiawakrim Guillaume Rogez Mohammed Benaissa Constantin Mihai Lucaciu Ovidiu Ersen |
| author_facet | Mohamed Alae Ait Kerroum Cristian Iacovita Walid Baaziz Dris Ihiawakrim Guillaume Rogez Mohammed Benaissa Constantin Mihai Lucaciu Ovidiu Ersen |
| author_sort | Mohamed Alae Ait Kerroum |
| collection | DOAJ |
| description | Superparamagnetic Zn<sub>x</sub>Fe<sub>3−x</sub>O<sub>4</sub> magnetic nanoparticles (0 ≤ x < 0.5) with spherical shapes of 16 nm average diameter and different zinc doping level have been successfully synthesized by co-precipitation method. The homogeneous zinc substitution of iron cations into the magnetite crystalline structure has led to an increase in the saturation magnetization of nanoparticles up to 120 Am<sup>2</sup>/kg for x ~ 0.3. The specific absorption rate (SAR) values increased considerably when x is varied between 0 and 0.3 and then decreased for x ~ 0.5. The SAR values are reduced upon the immobilization of the nanoparticles in a solid matrix being significantly increased by a pre-alignment step in a uniform static magnetic field before immobilization. The SAR values displayed a quadratic dependence on the alternating magnetic field amplitude (H) up to 35 kA/m. Above this value, a clear saturation effect of SAR was observed that was successfully described qualitatively and quantitatively by considering the non-linear field’s effects and the magnetic field dependence of both Brown and Neel relaxation times. The Neel relaxation time depends more steeply on H as compared with the Brown relaxation time, and the magnetization relaxation might be dominated by the Neel mechanism, even for nanoparticles with large diameter. |
| first_indexed | 2024-03-10T15:27:24Z |
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| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T15:27:24Z |
| publishDate | 2020-10-01 |
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| series | International Journal of Molecular Sciences |
| spelling | doaj.art-404c7a28ac3d4ace8be8369c17dbbc8f2023-11-20T17:53:49ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672020-10-012120777510.3390/ijms21207775Quantitative Analysis of the Specific Absorption Rate Dependence on the Magnetic Field Strength in Zn<sub>x</sub>Fe<sub>3−x</sub>O<sub>4</sub> NanoparticlesMohamed Alae Ait Kerroum0Cristian Iacovita1Walid Baaziz2Dris Ihiawakrim3Guillaume Rogez4Mohammed Benaissa5Constantin Mihai Lucaciu6Ovidiu Ersen7Institut de Physique et Chimie des Matériaux de Strasbourg (IPCMS), UMR 7504 CNRS-Université de Strasbourg, 23 rue du Loess BP 43, 67034 Strasbourg CEDEX 2, FranceDepartment of Pharmaceutical Physics-Biophysics, Faculty of Pharmacy, “Iuliu Hatieganu” University of Medicine and Pharmacy, Pasteur 6, 400349 Cluj-Napoca, RomaniaInstitut de Physique et Chimie des Matériaux de Strasbourg (IPCMS), UMR 7504 CNRS-Université de Strasbourg, 23 rue du Loess BP 43, 67034 Strasbourg CEDEX 2, FranceInstitut de Physique et Chimie des Matériaux de Strasbourg (IPCMS), UMR 7504 CNRS-Université de Strasbourg, 23 rue du Loess BP 43, 67034 Strasbourg CEDEX 2, FranceInstitut de Physique et Chimie des Matériaux de Strasbourg (IPCMS), UMR 7504 CNRS-Université de Strasbourg, 23 rue du Loess BP 43, 67034 Strasbourg CEDEX 2, FranceLaboratoire de Matière Condensée et Sciences Interdisciplinaires (LaMCScI), Faculty of Sciences, BP 1014 RP, Mohammed V University in Rabat, 10000 Rabat, MoroccoDepartment of Pharmaceutical Physics-Biophysics, Faculty of Pharmacy, “Iuliu Hatieganu” University of Medicine and Pharmacy, Pasteur 6, 400349 Cluj-Napoca, RomaniaInstitut de Physique et Chimie des Matériaux de Strasbourg (IPCMS), UMR 7504 CNRS-Université de Strasbourg, 23 rue du Loess BP 43, 67034 Strasbourg CEDEX 2, FranceSuperparamagnetic Zn<sub>x</sub>Fe<sub>3−x</sub>O<sub>4</sub> magnetic nanoparticles (0 ≤ x < 0.5) with spherical shapes of 16 nm average diameter and different zinc doping level have been successfully synthesized by co-precipitation method. The homogeneous zinc substitution of iron cations into the magnetite crystalline structure has led to an increase in the saturation magnetization of nanoparticles up to 120 Am<sup>2</sup>/kg for x ~ 0.3. The specific absorption rate (SAR) values increased considerably when x is varied between 0 and 0.3 and then decreased for x ~ 0.5. The SAR values are reduced upon the immobilization of the nanoparticles in a solid matrix being significantly increased by a pre-alignment step in a uniform static magnetic field before immobilization. The SAR values displayed a quadratic dependence on the alternating magnetic field amplitude (H) up to 35 kA/m. Above this value, a clear saturation effect of SAR was observed that was successfully described qualitatively and quantitatively by considering the non-linear field’s effects and the magnetic field dependence of both Brown and Neel relaxation times. The Neel relaxation time depends more steeply on H as compared with the Brown relaxation time, and the magnetization relaxation might be dominated by the Neel mechanism, even for nanoparticles with large diameter.https://www.mdpi.com/1422-0067/21/20/7775zinc doped iron oxide magnetic nanoparticlesco-precipitation methodmagnetic hyperthermiaspecific absorption rateLinear Response Theorysaturation of SAR |
| spellingShingle | Mohamed Alae Ait Kerroum Cristian Iacovita Walid Baaziz Dris Ihiawakrim Guillaume Rogez Mohammed Benaissa Constantin Mihai Lucaciu Ovidiu Ersen Quantitative Analysis of the Specific Absorption Rate Dependence on the Magnetic Field Strength in Zn<sub>x</sub>Fe<sub>3−x</sub>O<sub>4</sub> Nanoparticles International Journal of Molecular Sciences zinc doped iron oxide magnetic nanoparticles co-precipitation method magnetic hyperthermia specific absorption rate Linear Response Theory saturation of SAR |
| title | Quantitative Analysis of the Specific Absorption Rate Dependence on the Magnetic Field Strength in Zn<sub>x</sub>Fe<sub>3−x</sub>O<sub>4</sub> Nanoparticles |
| title_full | Quantitative Analysis of the Specific Absorption Rate Dependence on the Magnetic Field Strength in Zn<sub>x</sub>Fe<sub>3−x</sub>O<sub>4</sub> Nanoparticles |
| title_fullStr | Quantitative Analysis of the Specific Absorption Rate Dependence on the Magnetic Field Strength in Zn<sub>x</sub>Fe<sub>3−x</sub>O<sub>4</sub> Nanoparticles |
| title_full_unstemmed | Quantitative Analysis of the Specific Absorption Rate Dependence on the Magnetic Field Strength in Zn<sub>x</sub>Fe<sub>3−x</sub>O<sub>4</sub> Nanoparticles |
| title_short | Quantitative Analysis of the Specific Absorption Rate Dependence on the Magnetic Field Strength in Zn<sub>x</sub>Fe<sub>3−x</sub>O<sub>4</sub> Nanoparticles |
| title_sort | quantitative analysis of the specific absorption rate dependence on the magnetic field strength in zn sub x sub fe sub 3 x sub o sub 4 sub nanoparticles |
| topic | zinc doped iron oxide magnetic nanoparticles co-precipitation method magnetic hyperthermia specific absorption rate Linear Response Theory saturation of SAR |
| url | https://www.mdpi.com/1422-0067/21/20/7775 |
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