Selection of Candida albicans trisomy during oropharyngeal infection results in a commensal-like phenotype.
When the fungus Candida albicans proliferates in the oropharyngeal cavity during experimental oropharyngeal candidiasis (OPC), it undergoes large-scale genome changes at a much higher frequency than when it grows in vitro. Previously, we identified a specific whole chromosome amplification, trisomy...
Main Authors: | Anja Forche, Norma V Solis, Marc Swidergall, Robert Thomas, Alison Guyer, Annette Beach, Gareth A Cromie, Giang T Le, Emily Lowell, Norman Pavelka, Judith Berman, Aimeé M Dudley, Anna Selmecki, Scott G Filler |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-05-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1008137 |
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