Antioxidant Intervention Attenuates Aging-Related Changes in the Murine Ovary and Oocyte

Antioxidant Intervention Attenuates Aging-Related Changes in the Murine Ovary and Oocyte

Advanced maternal age (AMA) is associated with reduced fertility due in part to diminished ovarian follicle quantity, inferior oocyte quality, chromosome aneuploidy, and lower implantation rates. Ovarian aging is accompanied by increased oxidative stress and blunted antioxidant signaling, such that...

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Bibliographic Details
Main Authors: Mandy G. Katz-Jaffe, Sydney L. Lane, Jason C. Parks, Blair R. McCallie, Rachel Makloski, William B. Schoolcraft
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Life
Subjects:
antioxidants
flavonoids
oxidative stress
advanced maternal age
in vitro fertilization
dietary supplements
Online Access:https://www.mdpi.com/2075-1729/10/11/250

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