Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against a Wide Range of Insects
Thuringiensin (Thu), also known as β-exotoxin, is a thermostable secondary metabolite secreted by Bacillus thuringiensis. It has insecticidal activity against a wide range of insects, including species belonging to the orders Diptera, Coleoptera, Lepidoptera, Hymenoptera, Orthoptera, and Isoptera, a...
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| Format: | Article |
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MDPI AG
2014-07-01
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| Series: | Toxins |
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| Online Access: | http://www.mdpi.com/2072-6651/6/8/2229 |
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| author | Xiaoyan Liu Lifang Ruan Donghai Peng Lin Li Ming Sun Ziniu Yu |
| author_facet | Xiaoyan Liu Lifang Ruan Donghai Peng Lin Li Ming Sun Ziniu Yu |
| author_sort | Xiaoyan Liu |
| collection | DOAJ |
| description | Thuringiensin (Thu), also known as β-exotoxin, is a thermostable secondary metabolite secreted by Bacillus thuringiensis. It has insecticidal activity against a wide range of insects, including species belonging to the orders Diptera, Coleoptera, Lepidoptera, Hymenoptera, Orthoptera, and Isoptera, and several nematode species. The chemical formula of Thu is C22H32O19N5P, and it is composed of adenosine, glucose, phosphoric acid, and gluconic diacid. In contrast to the more frequently studied insecticidal crystal protein, Thu is not a protein but a small molecule oligosaccharide. In this review, a detailed and updated description of the characteristics, structure, insecticidal mechanism, separation and purification technology, and genetic determinants of Thu is provided. |
| first_indexed | 2024-04-13T06:57:38Z |
| format | Article |
| id | doaj.art-404feac0952142fcafb18ed138eadcf8 |
| institution | Directory Open Access Journal |
| issn | 2072-6651 |
| language | English |
| last_indexed | 2024-04-13T06:57:38Z |
| publishDate | 2014-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxins |
| spelling | doaj.art-404feac0952142fcafb18ed138eadcf82022-12-22T02:57:12ZengMDPI AGToxins2072-66512014-07-01682229223810.3390/toxins6082229toxins6082229Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against a Wide Range of InsectsXiaoyan Liu0Lifang Ruan1Donghai Peng2Lin Li3Ming Sun4Ziniu Yu5Hubei Biopesticide Engineering Research Center, Hubei Academy of Agricultural Sciences, Wuhan 430064, ChinaState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, ChinaState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, ChinaState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, ChinaState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, ChinaState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, ChinaThuringiensin (Thu), also known as β-exotoxin, is a thermostable secondary metabolite secreted by Bacillus thuringiensis. It has insecticidal activity against a wide range of insects, including species belonging to the orders Diptera, Coleoptera, Lepidoptera, Hymenoptera, Orthoptera, and Isoptera, and several nematode species. The chemical formula of Thu is C22H32O19N5P, and it is composed of adenosine, glucose, phosphoric acid, and gluconic diacid. In contrast to the more frequently studied insecticidal crystal protein, Thu is not a protein but a small molecule oligosaccharide. In this review, a detailed and updated description of the characteristics, structure, insecticidal mechanism, separation and purification technology, and genetic determinants of Thu is provided.http://www.mdpi.com/2072-6651/6/8/2229thuringiensinBacillus thuringiensisinsecticidal mechanismgenetic determinants |
| spellingShingle | Xiaoyan Liu Lifang Ruan Donghai Peng Lin Li Ming Sun Ziniu Yu Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against a Wide Range of Insects Toxins thuringiensin Bacillus thuringiensis insecticidal mechanism genetic determinants |
| title | Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against a Wide Range of Insects |
| title_full | Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against a Wide Range of Insects |
| title_fullStr | Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against a Wide Range of Insects |
| title_full_unstemmed | Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against a Wide Range of Insects |
| title_short | Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against a Wide Range of Insects |
| title_sort | thuringiensin a thermostable secondary metabolite from bacillus thuringiensis with insecticidal activity against a wide range of insects |
| topic | thuringiensin Bacillus thuringiensis insecticidal mechanism genetic determinants |
| url | http://www.mdpi.com/2072-6651/6/8/2229 |
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