Effect of Pharmacist-Led Interventions on Physicians’ Prescribing for Pediatric Outpatients
Background: Children are at high risk of drug-related problems, increased risk of treatment failures, and high treatment costs. We aimed to evaluate the effect of pharmacist-led interventions on physicians’ prescribing for pediatric outpatients. Methods: A prospective study with pre- and post-interv...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-04-01
|
| Series: | Healthcare |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9032/10/4/751 |
| _version_ | 1797446066386239488 |
|---|---|
| author | Kien Trung Nguyen Vy Tran Thanh Le Thao Huong Nguyen Suol Thanh Pham Phuong Minh Nguyen Katja Taxis Mai Tuyet Vi Thang Nguyen Hung Do Tran |
| author_facet | Kien Trung Nguyen Vy Tran Thanh Le Thao Huong Nguyen Suol Thanh Pham Phuong Minh Nguyen Katja Taxis Mai Tuyet Vi Thang Nguyen Hung Do Tran |
| author_sort | Kien Trung Nguyen |
| collection | DOAJ |
| description | Background: Children are at high risk of drug-related problems, increased risk of treatment failures, and high treatment costs. We aimed to evaluate the effect of pharmacist-led interventions on physicians’ prescribing for pediatric outpatients. Methods: A prospective study with pre- and post-intervention measurement assessment was conducted to collect pediatric outpatients’ prescriptions during the pre-intervention period (January 2020) and post-intervention (August 2020) at a children’s hospital in Vietnam. Drug-related problems were identified and categorized according to Pharmaceutical Care Network Europe (PCNE), version 9.1. The intervention program was developed based on the results of pre-intervention observations. After the intervention, prescriptions were evaluated. Statistical tests were used to compare the proportions of drug-related problems before and after the intervention and to identify factors related to drug-related problems. Results: There were 2788 out of 4218 (66.1%) prescriptions with at least one drug-related problem before the intervention. Of these drug-related problems, the most common was inappropriate timing of administration and incorrect dosage (36.1% and 35.6%, respectively). After the intervention, the percentage of prescriptions with at least one drug-related problem was 45.5% (<i>p</i> < 0.001). Most of the drug-related problem types decreased significantly (<i>p</i> < 0.05). The binary logistic regression analysis results showed that in addition to pharmacists’ intervention, patients’ gender, primary disease, comorbidity status, and the total number of drugs prescribed were also factors related to drug-related problems. Conclusions: Drug-related problems in pediatric outpatients were quite common. Pharmacists’ intervention helped to improve the prevalence and types of drug-related problems. |
| first_indexed | 2024-03-09T13:35:54Z |
| format | Article |
| id | doaj.art-405420e3e7e6404aa1073314e0551629 |
| institution | Directory Open Access Journal |
| issn | 2227-9032 |
| language | English |
| last_indexed | 2024-03-09T13:35:54Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Healthcare |
| spelling | doaj.art-405420e3e7e6404aa1073314e05516292023-11-30T21:12:23ZengMDPI AGHealthcare2227-90322022-04-0110475110.3390/healthcare10040751Effect of Pharmacist-Led Interventions on Physicians’ Prescribing for Pediatric OutpatientsKien Trung Nguyen0Vy Tran Thanh Le1Thao Huong Nguyen2Suol Thanh Pham3Phuong Minh Nguyen4Katja Taxis5Mai Tuyet Vi6Thang Nguyen7Hung Do Tran8Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho City 900000, VietnamDepartment of Pharmacy, Can Tho Children’s Hospital, Can Tho City 900000, VietnamDepartment of Clinical Pharmacy, School of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City 700000, VietnamDepartment of Pharmacology and Clinical Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho City 900000, VietnamFaculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho City 900000, VietnamGroningen Research Institute of Pharmacy, University of Groningen, 9713 AV Groningen, The NetherlandsDepartment of Pharmacology and Clinical Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho City 900000, VietnamDepartment of Pharmacology and Clinical Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho City 900000, VietnamFaculty of Nursing and Medical Technology, Can Tho University of Medicine and Pharmacy, Can Tho City 900000, VietnamBackground: Children are at high risk of drug-related problems, increased risk of treatment failures, and high treatment costs. We aimed to evaluate the effect of pharmacist-led interventions on physicians’ prescribing for pediatric outpatients. Methods: A prospective study with pre- and post-intervention measurement assessment was conducted to collect pediatric outpatients’ prescriptions during the pre-intervention period (January 2020) and post-intervention (August 2020) at a children’s hospital in Vietnam. Drug-related problems were identified and categorized according to Pharmaceutical Care Network Europe (PCNE), version 9.1. The intervention program was developed based on the results of pre-intervention observations. After the intervention, prescriptions were evaluated. Statistical tests were used to compare the proportions of drug-related problems before and after the intervention and to identify factors related to drug-related problems. Results: There were 2788 out of 4218 (66.1%) prescriptions with at least one drug-related problem before the intervention. Of these drug-related problems, the most common was inappropriate timing of administration and incorrect dosage (36.1% and 35.6%, respectively). After the intervention, the percentage of prescriptions with at least one drug-related problem was 45.5% (<i>p</i> < 0.001). Most of the drug-related problem types decreased significantly (<i>p</i> < 0.05). The binary logistic regression analysis results showed that in addition to pharmacists’ intervention, patients’ gender, primary disease, comorbidity status, and the total number of drugs prescribed were also factors related to drug-related problems. Conclusions: Drug-related problems in pediatric outpatients were quite common. Pharmacists’ intervention helped to improve the prevalence and types of drug-related problems.https://www.mdpi.com/2227-9032/10/4/751drug-related problemsoutpatientspediatricsprescribingVietnam |
| spellingShingle | Kien Trung Nguyen Vy Tran Thanh Le Thao Huong Nguyen Suol Thanh Pham Phuong Minh Nguyen Katja Taxis Mai Tuyet Vi Thang Nguyen Hung Do Tran Effect of Pharmacist-Led Interventions on Physicians’ Prescribing for Pediatric Outpatients Healthcare drug-related problems outpatients pediatrics prescribing Vietnam |
| title | Effect of Pharmacist-Led Interventions on Physicians’ Prescribing for Pediatric Outpatients |
| title_full | Effect of Pharmacist-Led Interventions on Physicians’ Prescribing for Pediatric Outpatients |
| title_fullStr | Effect of Pharmacist-Led Interventions on Physicians’ Prescribing for Pediatric Outpatients |
| title_full_unstemmed | Effect of Pharmacist-Led Interventions on Physicians’ Prescribing for Pediatric Outpatients |
| title_short | Effect of Pharmacist-Led Interventions on Physicians’ Prescribing for Pediatric Outpatients |
| title_sort | effect of pharmacist led interventions on physicians prescribing for pediatric outpatients |
| topic | drug-related problems outpatients pediatrics prescribing Vietnam |
| url | https://www.mdpi.com/2227-9032/10/4/751 |
| work_keys_str_mv | AT kientrungnguyen effectofpharmacistledinterventionsonphysiciansprescribingforpediatricoutpatients AT vytranthanhle effectofpharmacistledinterventionsonphysiciansprescribingforpediatricoutpatients AT thaohuongnguyen effectofpharmacistledinterventionsonphysiciansprescribingforpediatricoutpatients AT suolthanhpham effectofpharmacistledinterventionsonphysiciansprescribingforpediatricoutpatients AT phuongminhnguyen effectofpharmacistledinterventionsonphysiciansprescribingforpediatricoutpatients AT katjataxis effectofpharmacistledinterventionsonphysiciansprescribingforpediatricoutpatients AT maituyetvi effectofpharmacistledinterventionsonphysiciansprescribingforpediatricoutpatients AT thangnguyen effectofpharmacistledinterventionsonphysiciansprescribingforpediatricoutpatients AT hungdotran effectofpharmacistledinterventionsonphysiciansprescribingforpediatricoutpatients |