Ginaton reduces M1-polarized macrophages in hypertensive cardiac remodeling via NF-κB signaling

Ginaton reduces M1-polarized macrophages in hypertensive cardiac remodeling via NF-κB signaling

Introduction: Macrophages play a critical role in cardiac remodeling, and dysregulated macrophage polarization between the proinflammatory M1 and anti-inflammatory M2 phenotypes promotes excessive inflammation and cardiac damage. Ginaton is a natural extract extracted from Ginkgo biloba. Because of...

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Bibliographic Details
Main Authors: Jie Wang, Enze Cai, Xiangbo An, Junjie Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pharmacology
Subjects:
ginaton
inflammation
hypertension
cardiac remodeling
macrophage polarization
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1104871/full

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