A brief review of exercise, bipolar disorder and mechanistic pathways

Despite evidence that exercise has been found to be effective in the treatment of depression, it is unclear whether these data can be extrapolated to bipolar disorder. Available evidence for bipolar disorder is scant, with no existing randomised controlled trials having tested the impact of exercise...

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Main Authors: Daniel eThomson, Alyna eTurner, Sue eLauder, Margaret E Gigler, Lesley eBerk, Ajeet B Singh, Julie ePasco, Michael eBerk, Louisa eSylvia
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Psychology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyg.2015.00147/full
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author Daniel eThomson
Alyna eTurner
Alyna eTurner
Alyna eTurner
Sue eLauder
Margaret E Gigler
Lesley eBerk
Lesley eBerk
Ajeet B Singh
Julie ePasco
Julie ePasco
Michael eBerk
Michael eBerk
Michael eBerk
Michael eBerk
Louisa eSylvia
Louisa eSylvia
author_facet Daniel eThomson
Alyna eTurner
Alyna eTurner
Alyna eTurner
Sue eLauder
Margaret E Gigler
Lesley eBerk
Lesley eBerk
Ajeet B Singh
Julie ePasco
Julie ePasco
Michael eBerk
Michael eBerk
Michael eBerk
Michael eBerk
Louisa eSylvia
Louisa eSylvia
author_sort Daniel eThomson
collection DOAJ
description Despite evidence that exercise has been found to be effective in the treatment of depression, it is unclear whether these data can be extrapolated to bipolar disorder. Available evidence for bipolar disorder is scant, with no existing randomised controlled trials having tested the impact of exercise on depressive, manic or hypomanic symptomatology. Although exercise is often recommended in bipolar disorder, this is based on extrapolation from the unipolar literature, theory and clinical expertise and not empirical evidence. In addition, there are currently no available empirical data on program variables, with practical implications on frequency, intensity and type of exercise derived from unipolar depression studies. The aim of the current paper is to explore the relationship between exercise and bipolar disorder and potential mechanistic pathways. Given the high rate of medical co-morbidities experienced by people with bipolar disorder, it is possible that exercise is a potentially useful and important intervention with regard to general health benefits; however, further research is required to elucidate the impact of exercise on mood symptomology.
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spelling doaj.art-405cd9ffaa68486a8d2f0de922f03c0f2022-12-22T01:02:25ZengFrontiers Media S.A.Frontiers in Psychology1664-10782015-03-01610.3389/fpsyg.2015.00147122166A brief review of exercise, bipolar disorder and mechanistic pathwaysDaniel eThomson0Alyna eTurner1Alyna eTurner2Alyna eTurner3Sue eLauder4Margaret E Gigler5Lesley eBerk6Lesley eBerk7Ajeet B Singh8Julie ePasco9Julie ePasco10Michael eBerk11Michael eBerk12Michael eBerk13Michael eBerk14Louisa eSylvia15Louisa eSylvia16RMITDeakin UniversityUniversity of NewcastleUniversity of MelbourneFederation UniversityMassachusetts General HospitalDeakin UniversityDeakin UniversityDeakin UniversityDeakin UniversityUniversity of MelbourneDeakin UniversityUniversity of MelbourneFlorey Institute for Neuroscience and Mental HealthOrygen, The National Centre of Excellence in Youth Mental HealthMassachusetts General HospitalHarvard UniversityDespite evidence that exercise has been found to be effective in the treatment of depression, it is unclear whether these data can be extrapolated to bipolar disorder. Available evidence for bipolar disorder is scant, with no existing randomised controlled trials having tested the impact of exercise on depressive, manic or hypomanic symptomatology. Although exercise is often recommended in bipolar disorder, this is based on extrapolation from the unipolar literature, theory and clinical expertise and not empirical evidence. In addition, there are currently no available empirical data on program variables, with practical implications on frequency, intensity and type of exercise derived from unipolar depression studies. The aim of the current paper is to explore the relationship between exercise and bipolar disorder and potential mechanistic pathways. Given the high rate of medical co-morbidities experienced by people with bipolar disorder, it is possible that exercise is a potentially useful and important intervention with regard to general health benefits; however, further research is required to elucidate the impact of exercise on mood symptomology.http://journal.frontiersin.org/Journal/10.3389/fpsyg.2015.00147/fullBipolar DisorderDepressionExerciseNeurogenesishypomaniaMechanistic pathways
spellingShingle Daniel eThomson
Alyna eTurner
Alyna eTurner
Alyna eTurner
Sue eLauder
Margaret E Gigler
Lesley eBerk
Lesley eBerk
Ajeet B Singh
Julie ePasco
Julie ePasco
Michael eBerk
Michael eBerk
Michael eBerk
Michael eBerk
Louisa eSylvia
Louisa eSylvia
A brief review of exercise, bipolar disorder and mechanistic pathways
Frontiers in Psychology
Bipolar Disorder
Depression
Exercise
Neurogenesis
hypomania
Mechanistic pathways
title A brief review of exercise, bipolar disorder and mechanistic pathways
title_full A brief review of exercise, bipolar disorder and mechanistic pathways
title_fullStr A brief review of exercise, bipolar disorder and mechanistic pathways
title_full_unstemmed A brief review of exercise, bipolar disorder and mechanistic pathways
title_short A brief review of exercise, bipolar disorder and mechanistic pathways
title_sort brief review of exercise bipolar disorder and mechanistic pathways
topic Bipolar Disorder
Depression
Exercise
Neurogenesis
hypomania
Mechanistic pathways
url http://journal.frontiersin.org/Journal/10.3389/fpsyg.2015.00147/full
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