Repeated Application of Autologous Bone Marrow-Derived Lineage-Negative Stem/Progenitor Cells—Focus on Immunological Pathways in Patients with ALS

Repeated Application of Autologous Bone Marrow-Derived Lineage-Negative Stem/Progenitor Cells—Focus on Immunological Pathways in Patients with ALS

Therapeutic interventions in amyotrophic lateral sclerosis (ALS) are still far from satisfying. Immune modulating procedures raise hopes for slowing the disease progression. Stem cell therapies are believed to possess the ability to regulate innate and adaptive immune response and inflammation proce...

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Bibliographic Details
Main Authors: Bartłomiej Baumert, Anna Sobuś, Monika Gołąb-Janowska, Edyta Paczkowska, Karolina Łuczkowska, Dorota Rogińska, Alicja Zawiślak, Sławomir Milczarek, Bogumiła Osękowska, Wioletta Pawlukowska, Agnieszka Meller, Karolina Machowska-Sempruch, Agnieszka Wełnicka, Krzysztof Safranow, Przemysław Nowacki, Bogusław Machaliński
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
amyotrophic lateral sclerosis (ALS)
lineage-negative cells
immunological pathways
inflammatory response
neurotrophins
gene microarrays
Online Access:https://www.mdpi.com/2073-4409/9/8/1822

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