The Resistance Training Effects on Skeletal Muscle Stem Cells in Older Adult: A Systematic Review and Meta-Analysis
The objective of this systematic review and meta-analysis is to examine the effects of resistance exercise trainingon muscle stem cells in older adults. A database search was performed (PubMed, Scopus, Web of Science andGoogle Scholar) to identify controlled clinical trials in English language. The...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Royan Institute (ACECR), Tehran
2023-08-01
|
| Series: | Cell Journal |
| Subjects: | |
| Online Access: | https://www.celljournal.org/article_704814_27b716ed3f755bc7c842e8cf13db73d5.pdf |
| Summary: | The objective of this systematic review and meta-analysis is to examine the effects of resistance exercise trainingon muscle stem cells in older adults. A database search was performed (PubMed, Scopus, Web of Science andGoogle Scholar) to identify controlled clinical trials in English language. The mean difference (MD) with 95% confidenceintervals (CIs) and overall effect size were calculated for all comparisons. The PEDro scale was used to assess themethodological quality. Nineteen studies were included in the review. The meta-analysis found a significant effect ofresistance training (RT) on muscle stem cells in the elderly (difference in means=-0.008, Z=-3.415, P=0.001). Also,muscle stem cells changes were similar in men and women (difference in means=-0.004, Z=-1.558, P=0.119) andsignificant changes occur in type II muscle fibers (difference in means=-0.017, Z=-7.048, P=0.000). Resistance-typeexercise training significantly increased muscle stem cells content in intervention group that this result is similar in menand womenthis increase occurred more in type II muscle fibers. |
|---|---|
| ISSN: | 2228-5806 2228-5814 |