Effects of Low and High Aneurysmal Wall Shear Stress on Endothelial Cell Behavior: Differences and Similarities

Effects of Low and High Aneurysmal Wall Shear Stress on Endothelial Cell Behavior: Differences and Similarities

Background: Intracranial aneurysms (IAs) result from abnormal enlargement of the arterial lumen. IAs are mostly quiescent and asymptomatic, but their rupture leads to severe brain damage or death. As the evolution of IAs is hard to predict and intricates medical decision, it is essential to improve...

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Bibliographic Details
Main Authors: Sandrine Morel, Sabine Schilling, Mannekomba R. Diagbouga, Matteo Delucchi, Marie-Luce Bochaton-Piallat, Sylvain Lemeille, Sven Hirsch, Brenda R. Kwak
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Physiology
Subjects:
intracranial aneurysm
endothelial cell
wall shear stress
cell shape
differential gene expression
cytoskeleton
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.727338/full

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