CEP128 is involved in spermatogenesis in humans and mice

CEP128 is involved in spermatogenesis in humans and mice

CEP128 is a centrosomal protein important for the organization of centriolar microtubules. Here, the authors show that a CEP128 variant observed in human male siblings causes reduced sperm counts and morphologically abnormal sperm when modeled in mice, suggesting a role for CEP128 in male fertility.

Bibliographic Details
Main Authors: Xueguang Zhang, Lingbo Wang, Yongyi Ma, Yan Wang, Hongqian Liu, Mohan Liu, Lang Qin, Jinghong Li, Chuan Jiang, Xiaojian Zhang, Xudong Shan, Yuliang Liu, Jinsong Li, Yaqian Li, Rui Zheng, Yongkang Sun, Jianfeng Sun, Xiangyou Leng, Yan Liang, Feng Zhang, Xiaohui Jiang, Yihong Yang, Ying Shen
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-29109-7

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