Safety, Immunogenicity, and Effectiveness of Defective Viral Particles Arising in Mast Cells Against Influenza in Mice

Safety, Immunogenicity, and Effectiveness of Defective Viral Particles Arising in Mast Cells Against Influenza in Mice

Mast cells play pivotal roles in the pathogenesis of influenza A virus (IAV) infections. Defective viral particles (DPs) often arise during IAV replication, which can interfere with the replication of infectious viruses and stimulate the antiviral response of host cells. Therefore, DPs are expected...

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Bibliographic Details
Main Authors:	Caiyun Huo, Jijing Tian, Jinlong Cheng, Jin Xiao, Mingyong Chen, Shumei Zou, Haiyan Tian, Ming Wang, Huiling Sun, Yanxin Hu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-11-01
Series:	Frontiers in Immunology
Subjects:	H1N1 influenza A virus mast cells defective viral particles immunogenicity protective immune reaction
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2020.585254/full

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