The central pattern of weakness of ALS: Morphological correlates in whole‐body muscle MRI

Abstract Objective Monosynaptically cortically innervated α‐motoneurons are early and strongly involved in amyotrophic lateral sclerosis (ALS). Consequently, the muscles that receive the strongest direct corticomotoneuronal input are the clinically most affected. To objectify this concept in vivo th...

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Bibliographic Details
Main Authors: Nathalie Wimmer, Hans‐Peter Müller, Patrick Metze, Volker Rasche, Albert C. Ludolph, Jan Kassubek
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.52019