The Appearances of Brain Metastases of Small Cell Lung Cancer on 18F-FDG PET/CT
Purpose: We evaluate the appearances of the brain metastases (BMs) detected by brain magnetic resonance imaging (MRI) of small cell lung cancer (SCLC) on 18Fluor-Fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT). Patients and methods: SCLC patients who had an 18F...
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| Format: | Article |
| Language: | English |
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Selçuk University
2022-08-01
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| Series: | Genel Tıp Dergisi |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/2252601 |
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| author | Hasan Önner Farise Yılmaz Halil Özer Abdussamet Batur Gonca Kara Gedik |
| author_facet | Hasan Önner Farise Yılmaz Halil Özer Abdussamet Batur Gonca Kara Gedik |
| author_sort | Hasan Önner |
| collection | DOAJ |
| description | Purpose: We evaluate the appearances of the brain metastases (BMs) detected by brain magnetic resonance imaging (MRI) of small cell lung cancer (SCLC) on 18Fluor-Fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT).
Patients and methods: SCLC patients who had an 18F-FDG PET/CT scan and a brain MRI within 30 days for initial staging were included. MRI was used to detect BMs. The imaging results of BMs on 18F-FDG PET/CT were assessed. On the 18F-FDG PET/CT study, the BMs were classified as undetectable, hypometabolic, hypermetabolic, or mixed patterns (lesions with both hypermetabolic and hypometabolic parts).
Results: A total of 51 patients [48 (94.1%) of whom were male and 3 (5.9%) female, with an average age of 62.57 ± 9.64] were included in this study. Fifteen patients (29.4%) were in the limited stage, whereas 36 patients (69.6%) were in the extensive stage. In 11 individuals, MRI indicated 28 BMs. On 18F-FDG PET/CT, 13 of the 28 metastases were visible. The following were the BMs appearances on 18F-FDG PET/CT: hypometabolic (n: 4), hypermetabolic (n: 6), and mixed (n: 3). While the mean diameter of BMs detected in 18F-FDG PET/CT was 16mm; the mean diameter of undetected ones was 4.3 mm.
Conclusion: On 18F-FDG PET/CT, BMs can have a variety of appearances, including hypometabolic, hypermetabolic, and mixed patterns. On the other hand, failure to detect millimetric size BMs in 18F-FDG PET/CT prevents proper staging. |
| first_indexed | 2024-03-12T01:06:45Z |
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| id | doaj.art-408505b71b184fc796a0e5ce8b99e21a |
| institution | Directory Open Access Journal |
| issn | 2602-3741 |
| language | English |
| last_indexed | 2024-03-12T01:06:45Z |
| publishDate | 2022-08-01 |
| publisher | Selçuk University |
| record_format | Article |
| series | Genel Tıp Dergisi |
| spelling | doaj.art-408505b71b184fc796a0e5ce8b99e21a2023-09-14T08:47:58ZengSelçuk UniversityGenel Tıp Dergisi2602-37412022-08-0132327227510.54005/geneltip.1073349154The Appearances of Brain Metastases of Small Cell Lung Cancer on 18F-FDG PET/CTHasan Önner0Farise Yılmaz1Halil Özer2Abdussamet Batur3Gonca Kara Gedik4SELÇUK ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, NÜKLEER TIP ANABİLİM DALISELÇUK ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, NÜKLEER TIP ANABİLİM DALISELÇUK ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, RADYOLOJİ ANABİLİM DALISELÇUK ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, RADYOLOJİ ANABİLİM DALISELÇUK ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, NÜKLEER TIP ANABİLİM DALIPurpose: We evaluate the appearances of the brain metastases (BMs) detected by brain magnetic resonance imaging (MRI) of small cell lung cancer (SCLC) on 18Fluor-Fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT). Patients and methods: SCLC patients who had an 18F-FDG PET/CT scan and a brain MRI within 30 days for initial staging were included. MRI was used to detect BMs. The imaging results of BMs on 18F-FDG PET/CT were assessed. On the 18F-FDG PET/CT study, the BMs were classified as undetectable, hypometabolic, hypermetabolic, or mixed patterns (lesions with both hypermetabolic and hypometabolic parts). Results: A total of 51 patients [48 (94.1%) of whom were male and 3 (5.9%) female, with an average age of 62.57 ± 9.64] were included in this study. Fifteen patients (29.4%) were in the limited stage, whereas 36 patients (69.6%) were in the extensive stage. In 11 individuals, MRI indicated 28 BMs. On 18F-FDG PET/CT, 13 of the 28 metastases were visible. The following were the BMs appearances on 18F-FDG PET/CT: hypometabolic (n: 4), hypermetabolic (n: 6), and mixed (n: 3). While the mean diameter of BMs detected in 18F-FDG PET/CT was 16mm; the mean diameter of undetected ones was 4.3 mm. Conclusion: On 18F-FDG PET/CT, BMs can have a variety of appearances, including hypometabolic, hypermetabolic, and mixed patterns. On the other hand, failure to detect millimetric size BMs in 18F-FDG PET/CT prevents proper staging.https://dergipark.org.tr/tr/download/article-file/2252601küçük hücreli akciğer kanseripozitron emisyon tomografisibeyin metastazısmall cell lung cancerpositron emission tomographybrain metastasis |
| spellingShingle | Hasan Önner Farise Yılmaz Halil Özer Abdussamet Batur Gonca Kara Gedik The Appearances of Brain Metastases of Small Cell Lung Cancer on 18F-FDG PET/CT Genel Tıp Dergisi küçük hücreli akciğer kanseri pozitron emisyon tomografisi beyin metastazı small cell lung cancer positron emission tomography brain metastasis |
| title | The Appearances of Brain Metastases of Small Cell Lung Cancer on 18F-FDG PET/CT |
| title_full | The Appearances of Brain Metastases of Small Cell Lung Cancer on 18F-FDG PET/CT |
| title_fullStr | The Appearances of Brain Metastases of Small Cell Lung Cancer on 18F-FDG PET/CT |
| title_full_unstemmed | The Appearances of Brain Metastases of Small Cell Lung Cancer on 18F-FDG PET/CT |
| title_short | The Appearances of Brain Metastases of Small Cell Lung Cancer on 18F-FDG PET/CT |
| title_sort | appearances of brain metastases of small cell lung cancer on 18f fdg pet ct |
| topic | küçük hücreli akciğer kanseri pozitron emisyon tomografisi beyin metastazı small cell lung cancer positron emission tomography brain metastasis |
| url | https://dergipark.org.tr/tr/download/article-file/2252601 |
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