Bone, Brain, Heart study protocol: A resilient nested, tripartite prospective cohort study of the role of estrogen depletion on HIV pathology.

<h4>Purpose</h4>We describe the rationale for and design of an innovative, nested, tripartite prospective observational cohort study examining whether relative estrogen insufficiency-induced inflammation amplifies HIV-induced inflammation to cause end organ damage and worsen age-related...

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Bibliographic Details
Main Authors: C Christina Mehta, Kimberly S Hagen, Anna A Rubtsova, Cecile D Lahiri, Vasiliki Michopoulos, Caitlin A Moran, Lisa B Haddad, Kehmia Titanji, Lauren F Collins, Arshed A Quyyumi, Gretchen Neigh, Leslee J Shaw, M Neale Weitzmann, Lance Waller, Ighovwerha Ofotokun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0272608