Assistive System for Microinjection by Presenting Cell Deformation as Surface Tactile Sensation

Microinjection technology has been widely applied in various fields, including biology, medicine, and intracytoplasmic sperm injection (ICSI). In a typical ICSI environment, all tasks, such as determining the degree of extension, adjusting the depth of focus, finding polar bodies, and manipulating c...

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Main Authors: Sumiwa Saito, Tadayoshi Aoyama, Yuki Funabora, Masaru Takeuchi, Yasuhisa Hasegawa
Format: Article
Language:English
Published: IEEE 2024-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/10379610/
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author Sumiwa Saito
Tadayoshi Aoyama
Yuki Funabora
Masaru Takeuchi
Yasuhisa Hasegawa
author_facet Sumiwa Saito
Tadayoshi Aoyama
Yuki Funabora
Masaru Takeuchi
Yasuhisa Hasegawa
author_sort Sumiwa Saito
collection DOAJ
description Microinjection technology has been widely applied in various fields, including biology, medicine, and intracytoplasmic sperm injection (ICSI). In a typical ICSI environment, all tasks, such as determining the degree of extension, adjusting the depth of focus, finding polar bodies, and manipulating cells, rely only on visual information; therefore, the person performing ICSI should have particular skills. Consequently, ICSI is generally performed by embryologists specialized in embryo handling. However, with the recent growth in global demand for ICSI, there is a shortage of embryologists and lack of experience among embryologists, and a simple injection system that does not rely on skilled embryologists is required. In this study, we propose a micromanipulation interface that provides a surface tactile sensation with a fabric actuator based on the real-time image measurement of the degree of cell deformation to simplify our understanding of the cell state. The effectiveness of the proposed interface is verified through cell-puncture experiments conducted by novices and one expert.
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spelling doaj.art-4086edcebb464450a431ca122978d6c02024-01-10T00:05:59ZengIEEEIEEE Access2169-35362024-01-01123874388010.1109/ACCESS.2023.334916910379610Assistive System for Microinjection by Presenting Cell Deformation as Surface Tactile SensationSumiwa Saito0https://orcid.org/0009-0008-1237-6247Tadayoshi Aoyama1https://orcid.org/0000-0001-7860-0725Yuki Funabora2https://orcid.org/0000-0003-1477-9273Masaru Takeuchi3https://orcid.org/0000-0001-9304-4667Yasuhisa Hasegawa4https://orcid.org/0000-0001-9917-098XDepartment of Micro-Nano Mechanical Science and Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Aichi, JapanDepartment of Micro-Nano Mechanical Science and Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Aichi, JapanDepartment of Micro-Nano Mechanical Science and Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Aichi, JapanDepartment of Micro-Nano Mechanical Science and Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Aichi, JapanDepartment of Micro-Nano Mechanical Science and Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Aichi, JapanMicroinjection technology has been widely applied in various fields, including biology, medicine, and intracytoplasmic sperm injection (ICSI). In a typical ICSI environment, all tasks, such as determining the degree of extension, adjusting the depth of focus, finding polar bodies, and manipulating cells, rely only on visual information; therefore, the person performing ICSI should have particular skills. Consequently, ICSI is generally performed by embryologists specialized in embryo handling. However, with the recent growth in global demand for ICSI, there is a shortage of embryologists and lack of experience among embryologists, and a simple injection system that does not rely on skilled embryologists is required. In this study, we propose a micromanipulation interface that provides a surface tactile sensation with a fabric actuator based on the real-time image measurement of the degree of cell deformation to simplify our understanding of the cell state. The effectiveness of the proposed interface is verified through cell-puncture experiments conducted by novices and one expert.https://ieeexplore.ieee.org/document/10379610/Surface tactile sensationfabric actuatormicroinjection
spellingShingle Sumiwa Saito
Tadayoshi Aoyama
Yuki Funabora
Masaru Takeuchi
Yasuhisa Hasegawa
Assistive System for Microinjection by Presenting Cell Deformation as Surface Tactile Sensation
IEEE Access
Surface tactile sensation
fabric actuator
microinjection
title Assistive System for Microinjection by Presenting Cell Deformation as Surface Tactile Sensation
title_full Assistive System for Microinjection by Presenting Cell Deformation as Surface Tactile Sensation
title_fullStr Assistive System for Microinjection by Presenting Cell Deformation as Surface Tactile Sensation
title_full_unstemmed Assistive System for Microinjection by Presenting Cell Deformation as Surface Tactile Sensation
title_short Assistive System for Microinjection by Presenting Cell Deformation as Surface Tactile Sensation
title_sort assistive system for microinjection by presenting cell deformation as surface tactile sensation
topic Surface tactile sensation
fabric actuator
microinjection
url https://ieeexplore.ieee.org/document/10379610/
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AT tadayoshiaoyama assistivesystemformicroinjectionbypresentingcelldeformationassurfacetactilesensation
AT yukifunabora assistivesystemformicroinjectionbypresentingcelldeformationassurfacetactilesensation
AT masarutakeuchi assistivesystemformicroinjectionbypresentingcelldeformationassurfacetactilesensation
AT yasuhisahasegawa assistivesystemformicroinjectionbypresentingcelldeformationassurfacetactilesensation