Evaluation of the effects of progesterone on experimental Tooth movement in rabbits

Introduction: Bone turn over in females is influenced by steroid hormones such as progesterone. The aim of the present study was to evaluate the effects of Progesterone on experimental tooth movement in rabbits. Material and Methods: Twenty four pre-pubertal female albino rabbits were randomly assig...

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Main Authors: M Pousti, M Basafa, N Eslami
Format: Article
Language:fas
Published: Isfahan University of Medical Sciences 2009-01-01
Series:مجله دانشکده دندانپزشکی اصفهان
Subjects:
Online Access:http://jids.mui.ac.ir/index.php/jids/article/view/142
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author M Pousti
M Basafa
N Eslami
author_facet M Pousti
M Basafa
N Eslami
author_sort M Pousti
collection DOAJ
description Introduction: Bone turn over in females is influenced by steroid hormones such as progesterone. The aim of the present study was to evaluate the effects of Progesterone on experimental tooth movement in rabbits. Material and Methods: Twenty four pre-pubertal female albino rabbits were randomly assigned into three equal groups. In the first group (LTG), rabbits received daily injection of 5 mg intramuscular progesterone for 9 weeks. In the second group (STG), rabbits received the same injections for the last 3 weeks of the experiment and in the third or control group (CG), the animals did not receive any progesterone. At the end of the 6th week, in all groups, two brackets were bonded to the incisor teeth in order to apply 50 gr distal force to these teeth via a stainless steel springs. Measurements were conducted at the end of weeks 7, 8, and 9 to calculate the distance between the incisors. The ANOVA and Tukey tests were used to compare the three groups.Results: The results showed no significant difference between the three groups at the end of the 7th and 8th week, but at the end of the 9th week, the rate of tooth movement was significantly lower in the first group (long term progesterone application) compared to the other two groups (p value = 0.001 and 0.044, respectively). Conclusion: It was concluded that long- term Progesterone administration reduced the rate of tooth movement in rabbits. Key words: Progesterone, Tooth movement, Orthodontic treatment
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spelling doaj.art-40885394141a460f8b507ef8ed607dcb2023-08-02T02:35:26ZfasIsfahan University of Medical Sciencesمجله دانشکده دندانپزشکی اصفهان1735-255X2008-69892009-01-0144205209Evaluation of the effects of progesterone on experimental Tooth movement in rabbitsM PoustiM BasafaN EslamiIntroduction: Bone turn over in females is influenced by steroid hormones such as progesterone. The aim of the present study was to evaluate the effects of Progesterone on experimental tooth movement in rabbits. Material and Methods: Twenty four pre-pubertal female albino rabbits were randomly assigned into three equal groups. In the first group (LTG), rabbits received daily injection of 5 mg intramuscular progesterone for 9 weeks. In the second group (STG), rabbits received the same injections for the last 3 weeks of the experiment and in the third or control group (CG), the animals did not receive any progesterone. At the end of the 6th week, in all groups, two brackets were bonded to the incisor teeth in order to apply 50 gr distal force to these teeth via a stainless steel springs. Measurements were conducted at the end of weeks 7, 8, and 9 to calculate the distance between the incisors. The ANOVA and Tukey tests were used to compare the three groups.Results: The results showed no significant difference between the three groups at the end of the 7th and 8th week, but at the end of the 9th week, the rate of tooth movement was significantly lower in the first group (long term progesterone application) compared to the other two groups (p value = 0.001 and 0.044, respectively). Conclusion: It was concluded that long- term Progesterone administration reduced the rate of tooth movement in rabbits. Key words: Progesterone, Tooth movement, Orthodontic treatmenthttp://jids.mui.ac.ir/index.php/jids/article/view/142Key words: ProgesteroneTooth movementOrthodontic treatment
spellingShingle M Pousti
M Basafa
N Eslami
Evaluation of the effects of progesterone on experimental Tooth movement in rabbits
مجله دانشکده دندانپزشکی اصفهان
Key words: Progesterone
Tooth movement
Orthodontic treatment
title Evaluation of the effects of progesterone on experimental Tooth movement in rabbits
title_full Evaluation of the effects of progesterone on experimental Tooth movement in rabbits
title_fullStr Evaluation of the effects of progesterone on experimental Tooth movement in rabbits
title_full_unstemmed Evaluation of the effects of progesterone on experimental Tooth movement in rabbits
title_short Evaluation of the effects of progesterone on experimental Tooth movement in rabbits
title_sort evaluation of the effects of progesterone on experimental tooth movement in rabbits
topic Key words: Progesterone
Tooth movement
Orthodontic treatment
url http://jids.mui.ac.ir/index.php/jids/article/view/142
work_keys_str_mv AT mpousti evaluationoftheeffectsofprogesteroneonexperimentaltoothmovementinrabbits
AT mbasafa evaluationoftheeffectsofprogesteroneonexperimentaltoothmovementinrabbits
AT neslami evaluationoftheeffectsofprogesteroneonexperimentaltoothmovementinrabbits