Immune Checkpoint Therapy: Tumor Draining Lymph Nodes in the Spotlights
Tumor-draining lymph nodes play a paradoxical role in cancer. Surgeons often resect these sentinel lymph nodes to determine metastatic spread, thereby enabling prognosis and treatment. However, lymph nodes are vital organs for the orchestration of immune responses, due to the close encounters of ded...
Main Authors: | Marieke F. Fransen, Thorbald van Hall, Ferry Ossendorp |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-08-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/17/9401 |
Similar Items
-
Multi-scale characterization of tumor-draining lymph nodes in resectable lung cancer treated with neoadjuvant immune checkpoint inhibitors
by: Haitang Yang, et al.
Published: (2022-10-01) -
Role of tumor draining lymph nodes in generation of memory CD8+ T cells in a murine model of colon cancer
by: XIE Shuanglong, et al.
Published: (2023-04-01) -
A Physiologically Based Pharmacokinetic Framework for Quantifying Antibody Distribution Gradients from Tumors to Tumor-Draining Lymph Nodes
by: Eric Salgado, et al.
Published: (2022-04-01) -
Motility Dynamics of T Cells in Tumor-Draining Lymph Nodes: A Rational Indicator of Antitumor Response and Immune Checkpoint Blockade
by: Yasuhiro Kanda, et al.
Published: (2021-09-01) -
Is Pathologic Axillary Staging Valid If Lymph Nodes Are Less than 10 with Axillary Lymph Node Dissection after Neoadjuvant Chemotherapy?
by: Hee Jun Choi, et al.
Published: (2022-11-01)