Construction and Verification of Quality Evaluation Indicator System for Extracorporeal Membrane Oxygenation Animal Experimental Platform

ObjectiveTo establish a standardized and professional service quality evaluation index system for extracorporeal membrane oxygenation (ECMO) animal experimental platform. Methods The literature research and expert consultation were used to establish a factor set for the quality evaluation of EC...

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Main Authors: WANG Shuo, LÜ Yunhui, WANG Xiaokang, ZHANG Zhenhao, CUI Yongchun
Format: Article
Language:zho
Published: Editorial Office of Laboratory Animal and Comparative Medicine 2023-12-01
Series:Shiyan dongwu yu bijiao yixue
Subjects:
Online Access:https://www.slarc.org.cn/dwyx/CN/abstract/abstract5116.shtml
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author WANG Shuo
LÜ Yunhui
WANG Xiaokang
ZHANG Zhenhao
CUI Yongchun
author_facet WANG Shuo
LÜ Yunhui
WANG Xiaokang
ZHANG Zhenhao
CUI Yongchun
author_sort WANG Shuo
collection DOAJ
description ObjectiveTo establish a standardized and professional service quality evaluation index system for extracorporeal membrane oxygenation (ECMO) animal experimental platform. Methods The literature research and expert consultation were used to establish a factor set for the quality evaluation of ECMO animal experimental platform. Then, experts used the 1/9-9 scale method to compare and score pair-two indicators. Based on the principles of fuzzy analytic hierarchy process and expert scoring results, the ECMO animal experimental platform quality evaluation system was constructed. In order to verify the actual efficacy of this system, a case study was carried out on the ECMO animal experiment platform of FW Animal Experimental Center (FAEC) laboratory. Results A total of 10 experts were included in this study, the questionnaire recovery rate was 100%, the judgment coefficient (Ca) and familiarity coefficient (Cs) were both greater than 0.50, the expert authority was high (Cr>0.80), the validity test was P<0.01, and the coordination was good. The quality evaluation system of ECMO animal experiment platform includes two levels. There are 4 first-level indicators, with professionalism, safety, functionality, and stability ranked from high to low in terms of their weights. There are 15 second-level indicators, and the top 5 weights are personnel's technical expertise, attractiveness of hardware facility, auditability of data, confidentiality capabilities of data, and professionalism in service process. To facilitate the popularization and application of the system, this study also proposed a "star" system to represent the evaluation results of an ECMO animal experimental platform quality. The quality evaluation system established in this study was used to evaluate the FAEC laboratory as a case study, and the evaluation result was five-star. The actual potency value of FAEC laboratory was 0.910, reaching the five-star level, but the average actual appraisal values of "service continuity" and "sufficiency of project completion" were lower than 0.80, which needs to be improved. Conclusion A standardized and professional ECMO animal experimental platform quality evaluation system was established in this study, which would provide a measurable basis for the demander to select the supplier and a method for the supplier to complete the animal experiment of ECMO research and development with high quality.
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spelling doaj.art-408e2f11b5064874b4886afdd40a19a62024-01-16T10:58:49ZzhoEditorial Office of Laboratory Animal and Comparative MedicineShiyan dongwu yu bijiao yixue1674-58172023-12-0143660461110.12300/j.issn.1674-5817.2023.1071674-5817(2023)06-0604-08Construction and Verification of Quality Evaluation Indicator System for Extracorporeal Membrane Oxygenation Animal Experimental PlatformWANG Shuo0LÜ Yunhui1WANG Xiaokang2ZHANG Zhenhao3CUI Yongchun4Beijing Key Laboratory of Preclinical Research and Evaluation for Cardiovascular Implant Materials; State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases; Animal Experimental Center, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 102800, ChinaBeijing Key Laboratory of Preclinical Research and Evaluation for Cardiovascular Implant Materials; State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases; Animal Experimental Center, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 102800, ChinaBeijing Key Laboratory of Preclinical Research and Evaluation for Cardiovascular Implant Materials; State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases; Animal Experimental Center, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 102800, ChinaBeijing Key Laboratory of Preclinical Research and Evaluation for Cardiovascular Implant Materials; State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases; Animal Experimental Center, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 102800, ChinaBeijing Key Laboratory of Preclinical Research and Evaluation for Cardiovascular Implant Materials; State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases; Animal Experimental Center, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 102800, ChinaObjectiveTo establish a standardized and professional service quality evaluation index system for extracorporeal membrane oxygenation (ECMO) animal experimental platform. Methods The literature research and expert consultation were used to establish a factor set for the quality evaluation of ECMO animal experimental platform. Then, experts used the 1/9-9 scale method to compare and score pair-two indicators. Based on the principles of fuzzy analytic hierarchy process and expert scoring results, the ECMO animal experimental platform quality evaluation system was constructed. In order to verify the actual efficacy of this system, a case study was carried out on the ECMO animal experiment platform of FW Animal Experimental Center (FAEC) laboratory. Results A total of 10 experts were included in this study, the questionnaire recovery rate was 100%, the judgment coefficient (Ca) and familiarity coefficient (Cs) were both greater than 0.50, the expert authority was high (Cr>0.80), the validity test was P<0.01, and the coordination was good. The quality evaluation system of ECMO animal experiment platform includes two levels. There are 4 first-level indicators, with professionalism, safety, functionality, and stability ranked from high to low in terms of their weights. There are 15 second-level indicators, and the top 5 weights are personnel's technical expertise, attractiveness of hardware facility, auditability of data, confidentiality capabilities of data, and professionalism in service process. To facilitate the popularization and application of the system, this study also proposed a "star" system to represent the evaluation results of an ECMO animal experimental platform quality. The quality evaluation system established in this study was used to evaluate the FAEC laboratory as a case study, and the evaluation result was five-star. The actual potency value of FAEC laboratory was 0.910, reaching the five-star level, but the average actual appraisal values of "service continuity" and "sufficiency of project completion" were lower than 0.80, which needs to be improved. Conclusion A standardized and professional ECMO animal experimental platform quality evaluation system was established in this study, which would provide a measurable basis for the demander to select the supplier and a method for the supplier to complete the animal experiment of ECMO research and development with high quality.https://www.slarc.org.cn/dwyx/CN/abstract/abstract5116.shtmlextracorporeal membrane oxygenationanimal experimental platformquality evaluation
spellingShingle WANG Shuo
LÜ Yunhui
WANG Xiaokang
ZHANG Zhenhao
CUI Yongchun
Construction and Verification of Quality Evaluation Indicator System for Extracorporeal Membrane Oxygenation Animal Experimental Platform
Shiyan dongwu yu bijiao yixue
extracorporeal membrane oxygenation
animal experimental platform
quality evaluation
title Construction and Verification of Quality Evaluation Indicator System for Extracorporeal Membrane Oxygenation Animal Experimental Platform
title_full Construction and Verification of Quality Evaluation Indicator System for Extracorporeal Membrane Oxygenation Animal Experimental Platform
title_fullStr Construction and Verification of Quality Evaluation Indicator System for Extracorporeal Membrane Oxygenation Animal Experimental Platform
title_full_unstemmed Construction and Verification of Quality Evaluation Indicator System for Extracorporeal Membrane Oxygenation Animal Experimental Platform
title_short Construction and Verification of Quality Evaluation Indicator System for Extracorporeal Membrane Oxygenation Animal Experimental Platform
title_sort construction and verification of quality evaluation indicator system for extracorporeal membrane oxygenation animal experimental platform
topic extracorporeal membrane oxygenation
animal experimental platform
quality evaluation
url https://www.slarc.org.cn/dwyx/CN/abstract/abstract5116.shtml
work_keys_str_mv AT wangshuo constructionandverificationofqualityevaluationindicatorsystemforextracorporealmembraneoxygenationanimalexperimentalplatform
AT luyunhui constructionandverificationofqualityevaluationindicatorsystemforextracorporealmembraneoxygenationanimalexperimentalplatform
AT wangxiaokang constructionandverificationofqualityevaluationindicatorsystemforextracorporealmembraneoxygenationanimalexperimentalplatform
AT zhangzhenhao constructionandverificationofqualityevaluationindicatorsystemforextracorporealmembraneoxygenationanimalexperimentalplatform
AT cuiyongchun constructionandverificationofqualityevaluationindicatorsystemforextracorporealmembraneoxygenationanimalexperimentalplatform