Toxoplasmosis among blood donors: Unsafe blood transfusion in ibadan, southwest nigeria
BACKGROUND: In Nigeria, there is paucity of data on transfusion-transmissible parasitic infections that can cause post-transfusion illness, especially in immunocompromised and transfusion-dependent patients. This study was designed to bridge the gap by screening for Toxoplasma gondii which can be tr...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | Journal of Applied Hematology |
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| Online Access: | http://www.jahjournal.org/article.asp?issn=1658-5127;year=2019;volume=10;issue=4;spage=120;epage=125;aulast=Amoo |
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| author | Abimbola Amoo Kariuki Njaanake H O Dada-Adegbola Gloria Omosa-Manyonyi |
| author_facet | Abimbola Amoo Kariuki Njaanake H O Dada-Adegbola Gloria Omosa-Manyonyi |
| author_sort | Abimbola Amoo |
| collection | DOAJ |
| description | BACKGROUND: In Nigeria, there is paucity of data on transfusion-transmissible parasitic infections that can cause post-transfusion illness, especially in immunocompromised and transfusion-dependent patients. This study was designed to bridge the gap by screening for Toxoplasma gondii which can be transmitted by blood transfusion.
OBJECTIVES: The main objective of the study is to employ serology methods to screen blood donor's serum for T. gondii, in Blood Bank Transfusion Service Centre, Southwest Nigeria
MATERIALS AND METHODS: This is a cross-sectional study. Donor sera were tested for T. gondii infection using IgG and IgM enzyme-linked immunosorbent assay test kits.
RESULTS: A total of 248 donated blood sera were tested for T. gondii infection after storage. The seroprevalence of T.gondii IgG and IgM was 19.8% and 42.7%, respectively. There was a significant difference in anti-T. gondii IgM seroprevalence between vegetarian and generalists (3.2% vs. 40.8%; P < 0.002).
CONCLUSIONS: The anti-T. gondii IgM prevalence was relatively higher compared to anti-T. gondii IgG, implying the majority of seropositive donors had an acute or recent infection, might seroconvert to chronic infection. There was a lower seropositivity of T.gondii among vegetarian. |
| first_indexed | 2024-12-17T07:50:43Z |
| format | Article |
| id | doaj.art-408ebd11f98541a99ac2a50d41303f50 |
| institution | Directory Open Access Journal |
| issn | 1658-5127 |
| language | English |
| last_indexed | 2024-12-17T07:50:43Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Applied Hematology |
| spelling | doaj.art-408ebd11f98541a99ac2a50d41303f502022-12-21T21:57:52ZengWolters Kluwer Medknow PublicationsJournal of Applied Hematology1658-51272019-01-0110412012510.4103/joah.joah_31_19Toxoplasmosis among blood donors: Unsafe blood transfusion in ibadan, southwest nigeriaAbimbola AmooKariuki NjaanakeH O Dada-AdegbolaGloria Omosa-ManyonyiBACKGROUND: In Nigeria, there is paucity of data on transfusion-transmissible parasitic infections that can cause post-transfusion illness, especially in immunocompromised and transfusion-dependent patients. This study was designed to bridge the gap by screening for Toxoplasma gondii which can be transmitted by blood transfusion. OBJECTIVES: The main objective of the study is to employ serology methods to screen blood donor's serum for T. gondii, in Blood Bank Transfusion Service Centre, Southwest Nigeria MATERIALS AND METHODS: This is a cross-sectional study. Donor sera were tested for T. gondii infection using IgG and IgM enzyme-linked immunosorbent assay test kits. RESULTS: A total of 248 donated blood sera were tested for T. gondii infection after storage. The seroprevalence of T.gondii IgG and IgM was 19.8% and 42.7%, respectively. There was a significant difference in anti-T. gondii IgM seroprevalence between vegetarian and generalists (3.2% vs. 40.8%; P < 0.002). CONCLUSIONS: The anti-T. gondii IgM prevalence was relatively higher compared to anti-T. gondii IgG, implying the majority of seropositive donors had an acute or recent infection, might seroconvert to chronic infection. There was a lower seropositivity of T.gondii among vegetarian.http://www.jahjournal.org/article.asp?issn=1658-5127;year=2019;volume=10;issue=4;spage=120;epage=125;aulast=Amootransfusion-transmissible infectiontransfusion-transmitted toxoplasmosishaemoparasite |
| spellingShingle | Abimbola Amoo Kariuki Njaanake H O Dada-Adegbola Gloria Omosa-Manyonyi Toxoplasmosis among blood donors: Unsafe blood transfusion in ibadan, southwest nigeria Journal of Applied Hematology transfusion-transmissible infection transfusion-transmitted toxoplasmosis haemoparasite |
| title | Toxoplasmosis among blood donors: Unsafe blood transfusion in ibadan, southwest nigeria |
| title_full | Toxoplasmosis among blood donors: Unsafe blood transfusion in ibadan, southwest nigeria |
| title_fullStr | Toxoplasmosis among blood donors: Unsafe blood transfusion in ibadan, southwest nigeria |
| title_full_unstemmed | Toxoplasmosis among blood donors: Unsafe blood transfusion in ibadan, southwest nigeria |
| title_short | Toxoplasmosis among blood donors: Unsafe blood transfusion in ibadan, southwest nigeria |
| title_sort | toxoplasmosis among blood donors unsafe blood transfusion in ibadan southwest nigeria |
| topic | transfusion-transmissible infection transfusion-transmitted toxoplasmosis haemoparasite |
| url | http://www.jahjournal.org/article.asp?issn=1658-5127;year=2019;volume=10;issue=4;spage=120;epage=125;aulast=Amoo |
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