Plasma FGF21 concentrations are regulated by glucose independently of insulin and GLP-1 in lean, healthy humans

Background Fibroblast growth factor 21 (FGF21) treatment improves metabolic homeostasis in diverse species, including humans. Physiologically, plasma FGF21 levels increase modestly after glucose ingestion, but it is unclear whether this is mediated by glucose itself or due to a secondary effect of p...

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Bibliographic Details
Main Authors: Thomas P.J. Solomon, Steven Carter, Jacob M. Haus, Kristian Karstoft, Stephanie von Holstein-Rathlou, Mette S. Nielsen, Matthew P. Gillum
Format: Article
Language:English
Published: PeerJ Inc. 2022-01-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/12755.pdf