Chemical composition and antioxidant activity of Astragalus monspessulanus L. growing in semiarid areas of Algeria
This paper reports a phytochemical study of the aerial parts of Astragalus monspessulanus L. growing in Algeria. It deals with the isolation and structure elucidation of 13 known compounds. From the n-butanol extract, seven flavonoids 1–7, two saponins and one lignan were isolated. In addition, two...
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| Format: | Article |
| Language: | English |
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Serbian Chemical Society
2018-01-01
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| Series: | Journal of the Serbian Chemical Society |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0352-5139/2018/0352-51391700085B.pdf |
| _version_ | 1818551783006404608 |
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| author | Bourezzane Sawsen Haba Hamada Long Christophe Benkhaled Mohammed |
| author_facet | Bourezzane Sawsen Haba Hamada Long Christophe Benkhaled Mohammed |
| author_sort | Bourezzane Sawsen |
| collection | DOAJ |
| description | This paper reports a phytochemical study of the aerial parts of Astragalus monspessulanus L. growing in Algeria. It deals with the isolation and structure elucidation of 13 known compounds. From the n-butanol extract, seven flavonoids 1–7, two saponins and one lignan were isolated. In addition, two phytosterols and one triterpenoid were isolated from the ethyl acetate extract. The structures of all the isolated products were determined by using 1D and 2D-NMR techniques, measurement of optical rotation, mass spectrometry ESI-MS and by comparison with literature data. Furthermore, the antioxidant activity of the n-butanol extract of the aerial parts of Astragalus monspessulanus L. was investigated using the DPPH radical scavenging and ferrous ion chelating assays. The n-butanol extract showed low (EC50 = 2.09±0.434 mg mL-1) to moderate (IC50 = 63.60±0.01 μg mL-1) antioxidant activities depending on the test method. |
| first_indexed | 2024-12-12T09:04:29Z |
| format | Article |
| id | doaj.art-40953aef272c445c89438cbe6dc386a9 |
| institution | Directory Open Access Journal |
| issn | 0352-5139 1820-7421 |
| language | English |
| last_indexed | 2024-12-12T09:04:29Z |
| publishDate | 2018-01-01 |
| publisher | Serbian Chemical Society |
| record_format | Article |
| series | Journal of the Serbian Chemical Society |
| spelling | doaj.art-40953aef272c445c89438cbe6dc386a92022-12-22T00:29:42ZengSerbian Chemical SocietyJournal of the Serbian Chemical Society0352-51391820-74212018-01-01831313810.2298/JSC161212085B0352-51391700085BChemical composition and antioxidant activity of Astragalus monspessulanus L. growing in semiarid areas of AlgeriaBourezzane Sawsen0Haba Hamada1Long Christophe2Benkhaled Mohammed3Batna University, Faculty of Sciences, Department of Chemistry, Laboratory of Chemistry and Environmental Chemistry (L.C.C.E), AlgeriaBatna University, Faculty of Sciences, Department of Chemistry, Laboratory of Chemistry and Environmental Chemistry (L.C.C.E), AlgeriaUSR CNRS-Pierre Fabre, Toulouse, FranceBatna University, Faculty of Sciences, Department of Chemistry, Laboratory of Chemistry and Environmental Chemistry (L.C.C.E), AlgeriaThis paper reports a phytochemical study of the aerial parts of Astragalus monspessulanus L. growing in Algeria. It deals with the isolation and structure elucidation of 13 known compounds. From the n-butanol extract, seven flavonoids 1–7, two saponins and one lignan were isolated. In addition, two phytosterols and one triterpenoid were isolated from the ethyl acetate extract. The structures of all the isolated products were determined by using 1D and 2D-NMR techniques, measurement of optical rotation, mass spectrometry ESI-MS and by comparison with literature data. Furthermore, the antioxidant activity of the n-butanol extract of the aerial parts of Astragalus monspessulanus L. was investigated using the DPPH radical scavenging and ferrous ion chelating assays. The n-butanol extract showed low (EC50 = 2.09±0.434 mg mL-1) to moderate (IC50 = 63.60±0.01 μg mL-1) antioxidant activities depending on the test method.http://www.doiserbia.nb.rs/img/doi/0352-5139/2018/0352-51391700085B.pdfFabaceaeAstragalus monspessulanus L.flavonoidslignansaponinsNMRantioxidant activity |
| spellingShingle | Bourezzane Sawsen Haba Hamada Long Christophe Benkhaled Mohammed Chemical composition and antioxidant activity of Astragalus monspessulanus L. growing in semiarid areas of Algeria Journal of the Serbian Chemical Society Fabaceae Astragalus monspessulanus L. flavonoids lignan saponins NMR antioxidant activity |
| title | Chemical composition and antioxidant activity of Astragalus monspessulanus L. growing in semiarid areas of Algeria |
| title_full | Chemical composition and antioxidant activity of Astragalus monspessulanus L. growing in semiarid areas of Algeria |
| title_fullStr | Chemical composition and antioxidant activity of Astragalus monspessulanus L. growing in semiarid areas of Algeria |
| title_full_unstemmed | Chemical composition and antioxidant activity of Astragalus monspessulanus L. growing in semiarid areas of Algeria |
| title_short | Chemical composition and antioxidant activity of Astragalus monspessulanus L. growing in semiarid areas of Algeria |
| title_sort | chemical composition and antioxidant activity of astragalus monspessulanus l growing in semiarid areas of algeria |
| topic | Fabaceae Astragalus monspessulanus L. flavonoids lignan saponins NMR antioxidant activity |
| url | http://www.doiserbia.nb.rs/img/doi/0352-5139/2018/0352-51391700085B.pdf |
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