The Association of Chest CT-based Measurements with Myocardial Injury in Critically Ill Patients with COVID-19
Objective:Myocardial injury incidence is high in critically ill patients with coronavirus disease-2019 (COVID-19) and mortality increases in COVID-19 patients with myocardial injury. Our objective was to determine the association between chest computed tomography (CT)-based measurements and myocardi...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2023-06-01
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| Series: | Türk Yoğun Bakim Derneği Dergisi |
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| Online Access: |
http://www.turkishjic.org/archives/archive-detail/article-preview/the-association-of-chest-ct-based-measurements-wit/53105
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| _version_ | 1827921673841541120 |
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| author | Bişar Ergün Naciye Sinem Gezer Murat Küçük Mehmet Nuri Yakar Mehmet Celal Öztürk Muhittin Demir Erdem Yaka Bilgin Cömert Necati Gökmen Begüm Ergan |
| author_facet | Bişar Ergün Naciye Sinem Gezer Murat Küçük Mehmet Nuri Yakar Mehmet Celal Öztürk Muhittin Demir Erdem Yaka Bilgin Cömert Necati Gökmen Begüm Ergan |
| author_sort | Bişar Ergün |
| collection | DOAJ |
| description | Objective:Myocardial injury incidence is high in critically ill patients with coronavirus disease-2019 (COVID-19) and mortality increases in COVID-19 patients with myocardial injury. Our objective was to determine the association between chest computed tomography (CT)-based measurements and myocardial injury in critically ill patients with COVID-19.Materials and Methods:We conducted a single-center cohort study of patients admitted to the intensive care unit (ICU) with a diagnosis of COVID-19 who underwent chest CT. Myocardial injury was defined as high-sensitivity troponin I blood levels above the 99th percentile upper reference limit, independent of new abnormalities in electrocardiography and echocardiography. Demographic, clinical, laboratory results, and chest CT findings were collected at ICU admission.Results:A total of 213 patients were included. Of the 213 patients, 69 (32.4%) were female, and 144 (67.6%) were male. Myocardial injury incidence was 61.0% (n=130). Acute Physiology and Chronic Health Evaluation-II score [odds ratio (OR): 1.07, 95% confidence interval (CI): 1.02-1.12, p=0.005], having a chest CT severity score ≥18 (OR: 2.85, 95% CI: 1.29-6.32, p=0.010), having any coronary artery calcification (CAC) (OR: 2.45, 95% CI: 1.09-5.52, p=0.030), and age (OR: 1.04, 95% CI: 1.01-1.08, p=0.041), as factors independently associated with an increased risk of myocardial injury.Conclusion:The incidence of myocardial injury is high in critically ill COVID-19 patients. Chest CT severity score ≥18 and presence of CAC are practical and valuable tools readily available from existing chest CT to predict myocardial injury in critically ill patients with COVID-19. |
| first_indexed | 2024-03-13T04:30:48Z |
| format | Article |
| id | doaj.art-4095f604ae13411ab50a0a445173a2f8 |
| institution | Directory Open Access Journal |
| issn | 2146-6416 2147-267X |
| language | English |
| last_indexed | 2024-03-13T04:30:48Z |
| publishDate | 2023-06-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Yoğun Bakim Derneği Dergisi |
| spelling | doaj.art-4095f604ae13411ab50a0a445173a2f82023-06-19T13:15:21ZengGalenos YayineviTürk Yoğun Bakim Derneği Dergisi2146-64162147-267X2023-06-01212839210.4274/tybd.galenos.2022.3511913049054The Association of Chest CT-based Measurements with Myocardial Injury in Critically Ill Patients with COVID-19Bişar Ergün0Naciye Sinem Gezer1Murat Küçük2Mehmet Nuri Yakar3Mehmet Celal Öztürk4Muhittin Demir5Erdem Yaka6Bilgin Cömert7Necati Gökmen8Begüm Ergan9 Dokuz Eylül University Faculty of Medicine, Department of Internal Medicine, İzmir, Turkey Dokuz Eylül University Faculty of Medicine, Department of Radiology, İzmir, Turkey Dokuz Eylül University Faculty of Medicine, Department of Internal Medicine, İzmir, Turkey Dokuz Eylül University Faculty of Medicine, Department of Anesthesiology and Reanimation, Division of Intensive Care, İzmir, Turkey Dokuz Eylül University Faculty of Medicine, Department of Anesthesiology and Reanimation, Division of Intensive Care, İzmir, Turkey Dokuz Eylül University Faculty of Medicine, Department of Radiology, İzmir, Turkey Dokuz Eylül University Faculty of Medicine, Department of Neurology, İzmir, Turkey Dokuz Eylül University Faculty of Medicine, Department of Internal Medicine, İzmir, Turkey Dokuz Eylül University Faculty of Medicine, Department of Anesthesiology and Reanimation, Division of Intensive Care, İzmir, Turkey Dokuz Eylül University Faculty of Medicine, Department of Pulmonary, Division of Intensive Care, İzmir, Turkey Objective:Myocardial injury incidence is high in critically ill patients with coronavirus disease-2019 (COVID-19) and mortality increases in COVID-19 patients with myocardial injury. Our objective was to determine the association between chest computed tomography (CT)-based measurements and myocardial injury in critically ill patients with COVID-19.Materials and Methods:We conducted a single-center cohort study of patients admitted to the intensive care unit (ICU) with a diagnosis of COVID-19 who underwent chest CT. Myocardial injury was defined as high-sensitivity troponin I blood levels above the 99th percentile upper reference limit, independent of new abnormalities in electrocardiography and echocardiography. Demographic, clinical, laboratory results, and chest CT findings were collected at ICU admission.Results:A total of 213 patients were included. Of the 213 patients, 69 (32.4%) were female, and 144 (67.6%) were male. Myocardial injury incidence was 61.0% (n=130). Acute Physiology and Chronic Health Evaluation-II score [odds ratio (OR): 1.07, 95% confidence interval (CI): 1.02-1.12, p=0.005], having a chest CT severity score ≥18 (OR: 2.85, 95% CI: 1.29-6.32, p=0.010), having any coronary artery calcification (CAC) (OR: 2.45, 95% CI: 1.09-5.52, p=0.030), and age (OR: 1.04, 95% CI: 1.01-1.08, p=0.041), as factors independently associated with an increased risk of myocardial injury.Conclusion:The incidence of myocardial injury is high in critically ill COVID-19 patients. Chest CT severity score ≥18 and presence of CAC are practical and valuable tools readily available from existing chest CT to predict myocardial injury in critically ill patients with COVID-19. http://www.turkishjic.org/archives/archive-detail/article-preview/the-association-of-chest-ct-based-measurements-wit/53105 chest ct severity scorecoronary artery calcificationcritical careintensive care unitmyocardial injurysars-cov-2 |
| spellingShingle | Bişar Ergün Naciye Sinem Gezer Murat Küçük Mehmet Nuri Yakar Mehmet Celal Öztürk Muhittin Demir Erdem Yaka Bilgin Cömert Necati Gökmen Begüm Ergan The Association of Chest CT-based Measurements with Myocardial Injury in Critically Ill Patients with COVID-19 Türk Yoğun Bakim Derneği Dergisi chest ct severity score coronary artery calcification critical care intensive care unit myocardial injury sars-cov-2 |
| title | The Association of Chest CT-based Measurements with Myocardial Injury in Critically Ill Patients with COVID-19 |
| title_full | The Association of Chest CT-based Measurements with Myocardial Injury in Critically Ill Patients with COVID-19 |
| title_fullStr | The Association of Chest CT-based Measurements with Myocardial Injury in Critically Ill Patients with COVID-19 |
| title_full_unstemmed | The Association of Chest CT-based Measurements with Myocardial Injury in Critically Ill Patients with COVID-19 |
| title_short | The Association of Chest CT-based Measurements with Myocardial Injury in Critically Ill Patients with COVID-19 |
| title_sort | association of chest ct based measurements with myocardial injury in critically ill patients with covid 19 |
| topic | chest ct severity score coronary artery calcification critical care intensive care unit myocardial injury sars-cov-2 |
| url |
http://www.turkishjic.org/archives/archive-detail/article-preview/the-association-of-chest-ct-based-measurements-wit/53105
|
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