Enhanced Cytotoxicity for Colon 26 Cells Using Doxorubicin-Loaded Sorbitan Monooleate (Span 80) Vesicles

Enhanced Cytotoxicity for Colon 26 Cells Using Doxorubicin-Loaded Sorbitan Monooleate (Span 80) Vesicles

<p>Span 80 (sorbitan monooleate) vesicles behaved differently from conventional phospholipid vesicles (liposomes) because the former had a more fluid interface. After doxorubicin hydrochloride (DOX) was encapsulated into the Span 80 vesicle (loading efficiency: 63 %), DOX-loaded Span 80 vesicl...

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Bibliographic Details
Main Author: Keita Hayashi, Tsuyoshi Tatsui, Toshinori Shimanouchi, Hiroshi Umakoshi
Format: Article
Language:English
Published: Ivyspring International Publisher 2013-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v09p0142.htm

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