MRI Manifestions Correlate with Survival of Glioblastoma Multiforme Patients
<b>Objective</b> To identify the correlation between magnetic resonance manifestation and survival of patients with glioblastoma multiforme (GBM).<br><b>Methods</b> The magnetic resonance imaging (MRI) images of 30 glioblastoma patients were collected. Imaging features...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
China Anti-Cancer Association
2012-06-01
|
| Series: | Cancer Biology & Medicine |
| Subjects: | |
| Online Access: | http://www.cancerbiomed.org/index.php/cocr/article/view/19 |
| _version_ | 1818842599795982336 |
|---|---|
| author | Wen-bin Li Kai Tang Qian Chen Shuai Li Xiao-guang Qiu Shao-wu Li Tao Jiang |
| author_facet | Wen-bin Li Kai Tang Qian Chen Shuai Li Xiao-guang Qiu Shao-wu Li Tao Jiang |
| author_sort | Wen-bin Li |
| collection | DOAJ |
| description | <b>Objective</b> To identify the correlation between magnetic resonance manifestation and survival of patients with glioblastoma multiforme (GBM).<br><b>Methods</b> The magnetic resonance imaging (MRI) images of 30 glioblastoma patients were collected. Imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging were selected to determine their correlation with patient survival. The relationship between imaging and survival time was studied using SPSS 19.0 software. Kaplan-Meier survival analysis and log-rank test were used to compare the survival curves.<br><b>Results</b> Patients with ≤5% contrasted enhancement area of tumor had longer overall survival (OS) than those with >5% contrasted enhancement area of tumor. Patients without edema surrounding the tumor had longer OS than those with edema. Patients with tumor of hyperintensity and/or isointensity in T2-weighted imaging had longer OS than those with hyperintensity and/or isointensity and hypointensity.<br><b>Conclusions</b> Some MR imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging are correlated with the survival of patients with GBM. These features can serve as prognostic indicators for GBM patients. |
| first_indexed | 2024-12-19T04:44:32Z |
| format | Article |
| id | doaj.art-409d41fc757a44f29ea7c97486858082 |
| institution | Directory Open Access Journal |
| issn | 2095-3941 2095-3941 |
| language | English |
| last_indexed | 2024-12-19T04:44:32Z |
| publishDate | 2012-06-01 |
| publisher | China Anti-Cancer Association |
| record_format | Article |
| series | Cancer Biology & Medicine |
| spelling | doaj.art-409d41fc757a44f29ea7c974868580822022-12-21T20:35:31ZengChina Anti-Cancer AssociationCancer Biology & Medicine2095-39412095-39412012-06-019212012310.3969/j.issn.2095-3941.2012.02.0072012020007MRI Manifestions Correlate with Survival of Glioblastoma Multiforme PatientsWen-bin Li0Kai Tang1Qian Chen2Shuai Li3Xiao-guang Qiu4Shao-wu Li5Tao Jiang6Cancer Center, Beiing Shiitan Hospital, Capital Medical University, Beiing 100038, China;Department of Neurosurgery, Beiing Tiantan Hospital, Capital Medical University, Beiing 100050, China;Department of Neurosurgery, Beiing Tiantan Hospital, Capital Medical University, Beiing 100050, China;College of Public Health, Peking University, Beiing 100871, China;Department of Radiotherapy, Beiing Tiantan Hospital, Beiing 100050, China;Department of Radiology, Beiing Tiantan Hospital, Beiing 100050, ChinaDepartment of Neurosurgery, Beiing Tiantan Hospital, Capital Medical University, Beiing 100050, China;<b>Objective</b> To identify the correlation between magnetic resonance manifestation and survival of patients with glioblastoma multiforme (GBM).<br><b>Methods</b> The magnetic resonance imaging (MRI) images of 30 glioblastoma patients were collected. Imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging were selected to determine their correlation with patient survival. The relationship between imaging and survival time was studied using SPSS 19.0 software. Kaplan-Meier survival analysis and log-rank test were used to compare the survival curves.<br><b>Results</b> Patients with ≤5% contrasted enhancement area of tumor had longer overall survival (OS) than those with >5% contrasted enhancement area of tumor. Patients without edema surrounding the tumor had longer OS than those with edema. Patients with tumor of hyperintensity and/or isointensity in T2-weighted imaging had longer OS than those with hyperintensity and/or isointensity and hypointensity.<br><b>Conclusions</b> Some MR imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging are correlated with the survival of patients with GBM. These features can serve as prognostic indicators for GBM patients.http://www.cancerbiomed.org/index.php/cocr/article/view/19glioblastoma multiformediffusion magnetic resonance imagingsurvival |
| spellingShingle | Wen-bin Li Kai Tang Qian Chen Shuai Li Xiao-guang Qiu Shao-wu Li Tao Jiang MRI Manifestions Correlate with Survival of Glioblastoma Multiforme Patients Cancer Biology & Medicine glioblastoma multiforme diffusion magnetic resonance imaging survival |
| title | MRI Manifestions Correlate with Survival of Glioblastoma Multiforme Patients |
| title_full | MRI Manifestions Correlate with Survival of Glioblastoma Multiforme Patients |
| title_fullStr | MRI Manifestions Correlate with Survival of Glioblastoma Multiforme Patients |
| title_full_unstemmed | MRI Manifestions Correlate with Survival of Glioblastoma Multiforme Patients |
| title_short | MRI Manifestions Correlate with Survival of Glioblastoma Multiforme Patients |
| title_sort | mri manifestions correlate with survival of glioblastoma multiforme patients |
| topic | glioblastoma multiforme diffusion magnetic resonance imaging survival |
| url | http://www.cancerbiomed.org/index.php/cocr/article/view/19 |
| work_keys_str_mv | AT wenbinli mrimanifestionscorrelatewithsurvivalofglioblastomamultiformepatients AT kaitang mrimanifestionscorrelatewithsurvivalofglioblastomamultiformepatients AT qianchen mrimanifestionscorrelatewithsurvivalofglioblastomamultiformepatients AT shuaili mrimanifestionscorrelatewithsurvivalofglioblastomamultiformepatients AT xiaoguangqiu mrimanifestionscorrelatewithsurvivalofglioblastomamultiformepatients AT shaowuli mrimanifestionscorrelatewithsurvivalofglioblastomamultiformepatients AT taojiang mrimanifestionscorrelatewithsurvivalofglioblastomamultiformepatients |