Comprehensive analysis of transcription factor-based molecular subtypes and their correlation to clinical outcomes in small-cell lung cancerResearch in context

Comprehensive analysis of transcription factor-based molecular subtypes and their correlation to clinical outcomes in small-cell lung cancerResearch in context

Summary: Background: Recent studies have reported the predictive and prognostic value of novel transcriptional factor-based molecular subtypes in small-cell lung cancer (SCLC). We conducted an in-depth analysis pairing multi-omics data with immunohistochemistry (IHC) to elucidate the underlying cha...

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Bibliographic Details
Main Authors: Sehhoon Park, Tae Hee Hong, Soohyun Hwang, Simon Heeke, Carl M. Gay, Jiyeon Kim, Hyun-Ae Jung, Jong-Mu Sun, Jin Seok Ahn, Myung-Ju Ahn, Jong Ho Cho, Yong Soo Choi, Jhingook Kim, Young Mog Shim, Hong Kwan Kim, Lauren Averett Byers, John V. Heymach, Yoon-La Choi, Se-Hoon Lee, Keunchil Park
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:EBioMedicine
Subjects:
Small cell lung cancer
Molecular subtype
ASCL1
NEUROD1
POU2F3
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424000975

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