Synthesis and Evaluation of Antimicrobial Activity of the Rearranged Abietane Prattinin A and Its Synthetic Derivatives

Synthesis and Evaluation of Antimicrobial Activity of the Rearranged Abietane Prattinin A and Its Synthetic Derivatives

Synthesis of the natural product prattinin A and some new derivatives has been achieved using abietic acid. The final products and a selection of intermediates were evaluated for their antibacterial activity against three human pathogenic bacteria: <i>E. coli</i>, <i>P. aeruginosa&...

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Bibliographic Details
Main Authors: Mustapha Ait El Had, Manal Zefzoufi, Houda Zentar, Lahoucine Bahsis, Mouhi Eddine Hachim, Adib Ghaleb, Choukri Khelifa-Mahdjoubi, Hafida Bouamama, Ramón Alvarez-Manzaneda, José Justicia, Rachid Chahboun
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Molecules
Subjects:
natural product
abietane rearranged
prattinin A
antibacterial activity
ADMET
DFT calculation
Online Access:https://www.mdpi.com/1420-3049/29/3/650

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