Glibenclamide Prevents Diabetes in NOD Mice.

Glibenclamide Prevents Diabetes in NOD Mice.

Previous work has revealed that Cx36, the sole connexin expressed in the insulin-producing beta cells, enhances the secretion of insulin, and promotes the resistance of beta cells against pro-inflammatory cytokines. In parallel, the anti-diabetic sulphonylurea glibenclamide was shown to promote the...

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Bibliographic Details
Main Authors:	Smaragda Lamprianou, Conny Gysemans, Joanna Bou Saab, Helena Pontes, Chantal Mathieu, Paolo Meda
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2016-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC5178991?pdf=render

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