Cross-sectional study into age-related pathology of mouse models for limb girdle muscular dystrophy types 2D and 2F.

Cross-sectional study into age-related pathology of mouse models for limb girdle muscular dystrophy types 2D and 2F.

Limb girdle muscular dystrophy (LGMD) types 2D and 2F are caused by mutations in the genes encoding for α- and δ-sarcoglycan, respectively, leading to progressive muscle weakness. Mouse models exist for LGMD2D (Sgca-/-) and 2F (Sgcd-/-). In a previous natural history study, we described the patholog...

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Bibliographic Details
Main Authors: Ingrid E C Verhaart, Kayleigh Putker, Davy van de Vijver, Christa L Tanganyika-de Winter, Svetlana Pasteuning-Vuhman, Jaap J Plomp, Annemieke M Aartsma-Rus, Maaike van Putten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0220665

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