High-dimensional profiling of regulatory T cells in psoriasis reveals an impaired skin-trafficking propertyResearch in context

High-dimensional profiling of regulatory T cells in psoriasis reveals an impaired skin-trafficking propertyResearch in context

Summary: Background: Psoriasis is a chronic inflammatory skin disease with a Th17-skewed immune phenotype. Although it has been generally accepted that regulatory T cells (Tregs) in lesional psoriatic skin have functional impairment due to the local inflammatory microenvironment, the molecular prop...

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Bibliographic Details
Main Authors: Brian Hyohyoung Lee, Yoon Ji Bang, Sung Ha Lim, Seong-Jun Kang, Sung Hee Kim, Seunghee Kim-Schulze, Chung-Gyu Park, Hyun Je Kim, Tae-Gyun Kim
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:EBioMedicine
Subjects:
Chemokine receptors
Mass cytometry
Psoriasis
Regulatory T cells
Skin-trafficking
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424000203

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