Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues
An efficient protocol for the amination of 6-chloropurine derivatives through nucleophilic aromatic substitution under microwave irradiation was developed and applied to the synthesis in two steps of a series of new acyclic nucleosides (acyclovir analogues) starting from commercially available compo...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2005-02-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/10/2/508/ |
| _version_ | 1818306840989007872 |
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| author | H.-G. Schmalz A. Lanver |
| author_facet | H.-G. Schmalz A. Lanver |
| author_sort | H.-G. Schmalz |
| collection | DOAJ |
| description | An efficient protocol for the amination of 6-chloropurine derivatives through nucleophilic aromatic substitution under microwave irradiation was developed and applied to the synthesis in two steps of a series of new acyclic nucleosides (acyclovir analogues) starting from commercially available compounds. |
| first_indexed | 2024-12-13T06:48:53Z |
| format | Article |
| id | doaj.art-40a803cc62aa44eeb939d7b6fdb922ae |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-13T06:48:53Z |
| publishDate | 2005-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-40a803cc62aa44eeb939d7b6fdb922ae2022-12-21T23:56:11ZengMDPI AGMolecules1420-30492005-02-0110250851510.3390/10020508Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside AnaloguesH.-G. SchmalzA. LanverAn efficient protocol for the amination of 6-chloropurine derivatives through nucleophilic aromatic substitution under microwave irradiation was developed and applied to the synthesis in two steps of a series of new acyclic nucleosides (acyclovir analogues) starting from commercially available compounds.http://www.mdpi.com/1420-3049/10/2/508/Microwavenucleophilic aromatic substitutionnucleosides. |
| spellingShingle | H.-G. Schmalz A. Lanver Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues Molecules Microwave nucleophilic aromatic substitution nucleosides. |
| title | Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues |
| title_full | Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues |
| title_fullStr | Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues |
| title_full_unstemmed | Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues |
| title_short | Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues |
| title_sort | microwave assisted amination of a chloropurine derivative in the synthesis of acyclic nucleoside analogues |
| topic | Microwave nucleophilic aromatic substitution nucleosides. |
| url | http://www.mdpi.com/1420-3049/10/2/508/ |
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