Tetranuclear Polypyridylruthenium(II) Complexes as Selective Nucleic Acid Stains for Flow Cytometric Analysis of Monocytic and Epithelial Lung Carcinoma Large Extracellular Vesicles

Tetranuclear Polypyridylruthenium(II) Complexes as Selective Nucleic Acid Stains for Flow Cytometric Analysis of Monocytic and Epithelial Lung Carcinoma Large Extracellular Vesicles

Selective staining of extracellular vesicles (EVs) is a major challenge for diagnostic and therapeutic applications. Herein, the EV labeling properties of a new class of tetranuclear polypyridylruthenium(II) complexes, Rubb<sub>7</sub>-TNL and Rubb<sub>7</sub>-TL, as phosphor...

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Bibliographische Detailangaben
Hauptverfasser: Kartika Wardhani, Aviva Levina, Biyun Sun, Haipei Zou, Georges E. R. Grau, F. Richard Keene, J. Grant Collins, Peter A. Lay
Format: Artikel
Sprache:English
Veröffentlicht: MDPI AG 2024-06-01
Schriftenreihe:Biomolecules
Schlagworte:
ruthenium phosphorescent complexes
selective extracellular vesicle stain
microvesicles
flow cytometry
nucleic acids
Online Zugang:https://www.mdpi.com/2218-273X/14/6/664

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https://www.mdpi.com/2218-273X/14/6/664

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