Developing an m5C regulator–mediated RNA methylation modification signature to predict prognosis and immunotherapy efficacy in rectal cancer

Developing an m5C regulator–mediated RNA methylation modification signature to predict prognosis and immunotherapy efficacy in rectal cancer

BackgroundCurrently, a very small number of patients with colorectal cancer (CRC) respond to immune checkpoint inhibitor (ICI) treatment. Therefore, there is an urgent need to investigate effective biomarkers to determine the responsiveness to ICI treatment. Recently, aberrant 5-methylcytosine (m5C)...

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Bibliographic Details
Main Authors: Rixin Zhang, Wenqiang Gan, Jinbao Zong, Yufang Hou, Mingxuan Zhou, Zheng Yan, Tiegang Li, Silin Lv, Zifan Zeng, Weiqi Wang, Fang Zhang, Min Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
rectal cancer
prognosis
tumor immune microenvironment
immunotherapy
m5C RNA methylation regulator
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1054700/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1054700/full

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