Sex affects the response of Wistar rats to polyvinyl pyrrolidone (PVP)-coated silver nanoparticles in an oral 28 days repeated dose toxicity study

Sex affects the response of Wistar rats to polyvinyl pyrrolidone (PVP)-coated silver nanoparticles in an oral 28 days repeated dose toxicity study

Abstract Background Silver nanoparticles (AgNPs) are widely used in biomedicine due to their strong antimicrobial, antifungal, and antiviral activities. Concerns about their possible negative impacts on human and environmental health directed many researchers towards the assessment of the safety and...

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Main Authors: Marija Ćurlin, Rinea Barbir, Sanja Dabelić, Marija Ljubojević, Walter Goessler, Vedran Micek, Irena Žuntar, Mirela Pavić, Lucija Božičević, Ivan Pavičić, Ivana Vinković Vrček
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Particle and Fibre Toxicology
Subjects:
Accumulation
Toxicity
Oxidative stress
Metallothionein
Wistar rat
Online Access:https://doi.org/10.1186/s12989-021-00425-y

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