The splicing factor DHX38 enables retinal development through safeguarding genome integrity

The splicing factor DHX38 enables retinal development through safeguarding genome integrity

Summary: DEAH-Box Helicase 38 (DHX38) is a pre-mRNA splicing factor and also a disease-causing gene of autosomal recessive retinitis pigmentosa (arRP). The role of DHX38 in the development and maintenance of the retina remains largely unknown. In this study, by using the dhx38 knockout zebrafish mod...

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Bibliographic Details
Main Authors: Kui Sun, Yunqiao Han, Jingzhen Li, Shanshan Yu, Yuwen Huang, Yangjun Zhang, Jamas Reilly, Jiayi Tu, Pan Gao, Danna Jia, Xiang Chen, Hualei Hu, Mengmeng Ren, Pei Li, Jiong Luo, Xiang Ren, Xianqin Zhang, Xinhua Shu, Fei Liu, Mugen Liu, Zhaohui Tang
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:iScience
Subjects:
Molecular physiology
Developmental genetics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223021806

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