Drug-free in vitro activation for primary ovarian insufficiency
Primary Ovarian Insufficiency (POI) or Diminished Ovarian Reserve (DOR) are the two conditions that affects women leading to infertility due to the lack of follicular growth and ovulation. Egg / Oocyte donation remains an option for these patients. However, with the development in Reproductive medic...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Journal of Human Reproductive Sciences |
| Subjects: | |
| Online Access: | http://www.jhrsonline.org/article.asp?issn=0974-1208;year=2021;volume=14;issue=4;spage=443;epage=445;aulast=Patel |
| _version_ | 1798033760554319872 |
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| author | Niket H Patel Harsha K Bhadarka Nayana H Patel Molina Niket Patel |
| author_facet | Niket H Patel Harsha K Bhadarka Nayana H Patel Molina Niket Patel |
| author_sort | Niket H Patel |
| collection | DOAJ |
| description | Primary Ovarian Insufficiency (POI) or Diminished Ovarian Reserve (DOR) are the two conditions that affects women leading to infertility due to the lack of follicular growth and ovulation. Egg / Oocyte donation remains an option for these patients. However, with the development in Reproductive medicine various novel technologies like Ovarian Cryopreservation, Fragmentation, in vitro activation with drug treatment or even drug free autotransplantation enables the possibility of activating the pool of primordial follicles that can lead to successful pregnancy outcomes. Here, we report a case of women with POI, in which drug free in vitro activation of follicles was performed, followed by autotransplantation, which resulted in successful pregnancy. This is first case report from India that shows the procedure works and can be tried for women with POI. |
| first_indexed | 2024-04-11T20:35:02Z |
| format | Article |
| id | doaj.art-40b0df39fbf344d5bdb9111cd9662a92 |
| institution | Directory Open Access Journal |
| issn | 0974-1208 1998-4766 |
| language | English |
| last_indexed | 2024-04-11T20:35:02Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Human Reproductive Sciences |
| spelling | doaj.art-40b0df39fbf344d5bdb9111cd9662a922022-12-22T04:04:24ZengWolters Kluwer Medknow PublicationsJournal of Human Reproductive Sciences0974-12081998-47662021-01-0114444344510.4103/jhrs.jhrs_56_21Drug-free in vitro activation for primary ovarian insufficiencyNiket H PatelHarsha K BhadarkaNayana H PatelMolina Niket PatelPrimary Ovarian Insufficiency (POI) or Diminished Ovarian Reserve (DOR) are the two conditions that affects women leading to infertility due to the lack of follicular growth and ovulation. Egg / Oocyte donation remains an option for these patients. However, with the development in Reproductive medicine various novel technologies like Ovarian Cryopreservation, Fragmentation, in vitro activation with drug treatment or even drug free autotransplantation enables the possibility of activating the pool of primordial follicles that can lead to successful pregnancy outcomes. Here, we report a case of women with POI, in which drug free in vitro activation of follicles was performed, followed by autotransplantation, which resulted in successful pregnancy. This is first case report from India that shows the procedure works and can be tried for women with POI.http://www.jhrsonline.org/article.asp?issn=0974-1208;year=2021;volume=14;issue=4;spage=443;epage=445;aulast=Pateldrug-freein vitro activationinfertility |
| spellingShingle | Niket H Patel Harsha K Bhadarka Nayana H Patel Molina Niket Patel Drug-free in vitro activation for primary ovarian insufficiency Journal of Human Reproductive Sciences drug-free in vitro activation infertility |
| title | Drug-free in vitro activation for primary ovarian insufficiency |
| title_full | Drug-free in vitro activation for primary ovarian insufficiency |
| title_fullStr | Drug-free in vitro activation for primary ovarian insufficiency |
| title_full_unstemmed | Drug-free in vitro activation for primary ovarian insufficiency |
| title_short | Drug-free in vitro activation for primary ovarian insufficiency |
| title_sort | drug free in vitro activation for primary ovarian insufficiency |
| topic | drug-free in vitro activation infertility |
| url | http://www.jhrsonline.org/article.asp?issn=0974-1208;year=2021;volume=14;issue=4;spage=443;epage=445;aulast=Patel |
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