AAV-mediated human PEDF inhibits tumor growth and metastasis in murine colorectal peritoneal carcinomatosis model

AAV-mediated human PEDF inhibits tumor growth and metastasis in murine colorectal peritoneal carcinomatosis model

<p>Abstract</p> <p>Background</p> <p>Angiogenesis plays an important role in tumor growth and metastasis, therefore antiangiogenic therapy was widely investigated as a promising approach for cancer therapy. Recently, pigment epithelium-derived factor (PEDF) has been sho...

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Bibliographic Details
Main Authors: Wu Qin Jie, Gong Chang Yang, Luo Shun Tao, Zhang Dong Mei, Zhang Shuang, Shi Hua Shan, Lu Lian, Yan Heng Xiu, He Sha Sha, Li Dan Dan, Yang Li, Zhao Xia, Wei Yu Quan
Format: Article
Language:English
Published: BMC 2012-03-01
Series:BMC Cancer
Subjects:
AAV
PEDF
Tumor
Antiangiogesis
Gene therapy
Online Access:http://www.biomedcentral.com/1471-2407/12/129

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