Regulation of Cardiac Fibroblast GLS1 Expression by Scleraxis

Regulation of Cardiac Fibroblast GLS1 Expression by Scleraxis

Fibrosis is an energy-intensive process requiring the activation of fibroblasts to myofibroblasts, resulting in the increased synthesis of extracellular matrix proteins. Little is known about the transcriptional control of energy metabolism in cardiac fibroblast activation, but glutaminolysis has be...

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Bibliographic Details
Main Authors: Sikta Chattopadhyaya, Raghu S. Nagalingam, D. Allison Ledingham, Teri L. Moffatt, Danah S. Al-Hattab, Pavit Narhan, Matthew T. Stecy, Kimberley A. O’Hara, Michael P. Czubryt
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
cardiac fibrosis
energy metabolism
fibroblast
myofibroblast
glutaminolysis
transcription
Online Access:https://www.mdpi.com/2073-4409/11/9/1471

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