Role of mitochondria and cardiolipins in growth inhibition of breast cancer cells by retinoic acid

Role of mitochondria and cardiolipins in growth inhibition of breast cancer cells by retinoic acid

Abstract Background All-trans-retinoic-acid (ATRA) is a promising agent in the prevention/treatment of breast-cancer. There is growing evidence that reprogramming of cellular lipid metabolism contributes to malignant transformation and progression. Lipid metabolism is implicated in cell differentiat...

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Bibliographic Details
Main Authors: Mineko Terao, Laura Goracci, Valentina Celestini, Mami Kurosaki, Marco Bolis, Alessandra Di Veroli, Arianna Vallerga, Maddalena Fratelli, Monica Lupi, Alessandro Corbelli, Fabio Fiordaliso, Maurizio Gianni, Gabriela Paroni, Adriana Zanetti, Gabriele Cruciani, Enrico Garattini
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Retinoic acid
Breast cancer
Lipidomics
Oxidative phosphorylation
Online Access:http://link.springer.com/article/10.1186/s13046-019-1438-y

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