Sorafenib as an Inhibitor of RUVBL2

Sorafenib as an Inhibitor of RUVBL2

RUVBL1 and RUVBL2 are highly conserved ATPases that belong to the AAA+ (ATPases Associated with various cellular Activities) superfamily and are involved in various complexes and cellular processes, several of which are closely linked to oncogenesis. The proteins were implicated in DNA damage signal...

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Bibliographic Details
Main Authors: Nardin Nano, Francisca Ugwu, Thiago V. Seraphim, Tangzhi Li, Gina Azer, Methvin Isaac, Michael Prakesch, Leandro R. S. Barbosa, Carlos H. I. Ramos, Alessandro Datti, Walid A. Houry
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Biomolecules
Subjects:
RUVBL2
RUVBL1
Sorafenib
AAA+ proteins
Inhibition
Online Access:https://www.mdpi.com/2218-273X/10/4/605

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