4573 Characterization of vascular disease in an Acta2 mutant mouse model

OBJECTIVES/GOALS: ACTA2 R179 carriers present with early-onset stroke; occlusive lesions of the distal internal carotid artery and branches are filled with cells staining positive for smooth muscle cell (SMC) markers. We will identify pathways leading to increased SMC proliferation and migration and...

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Bibliographic Details
Main Authors: Anita Kaw, Callie Kwartler, Abhijnan Chattopadhyay, Dianna M. Milewicz
Format: Article
Language:English
Published: Cambridge University Press 2020-06-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866120003751/type/journal_article

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