Association of MICA gene polymorphisms with liver fibrosis in schistosomiasis patients in the Dongting Lake region

Association of MICA gene polymorphisms with liver fibrosis in schistosomiasis patients in the Dongting Lake region

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Major histocompatibility complex class I chain-related A (MICA) is a highly polymorphic gene located within the MHC class I region of the human genome. Expressed as a cell surface glycoprotein, MICA modulates immune surveillance by binding to its cognate receptor on natural killer cells, NKG2D, and...

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Bibliographic Details
Main Authors: Zheng Gong, Qi-Zhi Luo, Lin Lin, Yu-Ping Su, Hai-Bo Peng, Kun Du, Ping Yu, Shi-Ping Wang
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2012-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Schistosoma japonicum
MICA
NKG2D
Gene polymorphism
Liver fibrosis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000300007

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000300007

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