Breath-Synchronized Nebulized Surfactant in a Porcine Model of Acute Respiratory Distress Syndrome

Objectives:. Effective treatment options for surfactant therapy in acute respiratory distress syndrome and coronavirus disease 2019 have not been established. To conduct preclinical studies in vitro and in vivo to evaluate efficiency, particle size, dosing, safety, and efficacy of inhaled surfactant...

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Main Authors: Robert M. DiBlasi, RRT-NPS, FAARC, Masaki Kajimoto, MD, PhD, Jonathan A. Poli, MS, Gail Deutsch, MD, Juergen Pfeiffer, MS, Joseph Zimmerman, RRT-NPS, David N. Crotwell, MHL, RRT-NPS, Patrik Malone, RRT, James B. Fink, RRT-NPS, PhD, Coral Ringer, RN, Rajesh Uthamanthil, DVM, PhD, Dolena Ledee, PhD, Michael A. Portman, MD
Format: Article
Language:English
Published: Wolters Kluwer 2021-02-01
Series:Critical Care Explorations
Online Access:http://journals.lww.com/10.1097/CCE.0000000000000338