Cardiopulmonary bypass alters the pharmacokinetics of propranolol in patients undergoing cardiac surgery

Cardiopulmonary bypass alters the pharmacokinetics of propranolol in patients undergoing cardiac surgery

The pharmacokinetics of propranolol may be altered by hypothermic cardiopulmonary bypass (CPB), resulting in unpredictable postoperative hemodynamic responses to usual doses. The objective of the present study was to investigate the pharmacokinetics of propranolol in patients undergoing coronary art...

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Bibliographic Details
Main Authors: M.J.C. Carmona, L.M.S. Malbouisson, V.A. Pereira, M.A. Bertoline, C.E.K. Omosako, K.B. Le Bihan, J.O.C. Auler Jr., S.R.C.J. Santos
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2005-05-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Propranolol
Pharmacokinetics
Cardiopulmonary bypass
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000500008

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