COMPARISON OF WORLD HEALTH ORGANIZATION TREATMENT FOR ACUTE WATERY DIARRHEA IN CHILDREN WITH AND WITHOUT SACCHROMYCES BOULARDII IN TERMS OF MEAN DURATION OF DIARRHEA
Objective: To compare World Health Organization treatment for acute watery diarrhea in children with and without probiotic Saccharomyces boulardii in terms of mean duration of diarrhea. Study Design: Comparative cross sectional study. Place and Duration of Study: Combined Military Hospital Tar...
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| Format: | Article |
| Language: | English |
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Army Medical College Rawalpindi
2020-10-01
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| Series: | Pakistan Armed Forces Medical Journal |
| Subjects: | |
| Online Access: | https://www.pafmj.org/index.php/PAFMJ/article/view/5566/2969 |
| _version_ | 1830190930867519488 |
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| author | Ali Raza Muhammad Zahid Ehsan Qadir Nazir Ahmed Malik Sohail Aslam Kashif Siddique |
| author_facet | Ali Raza Muhammad Zahid Ehsan Qadir Nazir Ahmed Malik Sohail Aslam Kashif Siddique |
| author_sort | Ali Raza |
| collection | DOAJ |
| description | Objective: To compare World Health Organization treatment for acute watery diarrhea in children with and without probiotic Saccharomyces boulardii in terms of mean duration of diarrhea.
Study Design: Comparative cross sectional study.
Place and Duration of Study: Combined Military Hospital Tarbela, Pakistan, from Jan 2019 to Jul 2019.
Methodology: Eighty four children were enrolled in this study using inclusion and exclusion criteria. Two groups were made. Group A was treated with oral Zinc (10mg for <6 months old, 20mg for >6 months old for 14 days); low osmolarity Oral rehydration salt by 5 ml/kg per hour and continuation of nutritious feeding. Group B was treated with 250mg twice daily Sacchromyces boulardii along with oral Zinc (10mg for <6months old, 20mg for >6 months old for 14 days); low osmolarity Oral rehydration salt by 5 ml/kg per hour and continuation of nutritious feeding. Assessment included anthropometric measurements, hydration status, daily frequency and consistency of stools. Baseline investigations were sent to Combined Military Hospital, Tarbela Laboratory. Data was recorded on a specially designed proforma.
Results: Duration of diarrhea was significantly lower in children who were given Saccharomyces boulardii with Zinc as compared to children who were given Zinc alone. i.e., group-A (Zinc): 53.31 hrs vs. group-B (Zinc+ Saccharomyces boulardii): 36.37 hrs, p<0.001
Conclusion: Saccharomyces boulardii can be effectively used with Zinc to treat acute watery diarrhea in children less than five years of age as it significantly reduces mean duration of diarrhea. |
| first_indexed | 2024-12-17T23:29:32Z |
| format | Article |
| id | doaj.art-40d05f1a33b149529ed2f737c28faf46 |
| institution | Directory Open Access Journal |
| issn | 0030-9648 2411-8842 |
| language | English |
| last_indexed | 2024-12-17T23:29:32Z |
| publishDate | 2020-10-01 |
| publisher | Army Medical College Rawalpindi |
| record_format | Article |
| series | Pakistan Armed Forces Medical Journal |
| spelling | doaj.art-40d05f1a33b149529ed2f737c28faf462022-12-21T21:28:41ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422020-10-0170513711375COMPARISON OF WORLD HEALTH ORGANIZATION TREATMENT FOR ACUTE WATERY DIARRHEA IN CHILDREN WITH AND WITHOUT SACCHROMYCES BOULARDII IN TERMS OF MEAN DURATION OF DIARRHEAAli Raza0Muhammad Zahid1Ehsan Qadir2Nazir Ahmed Malik3Sohail Aslam4Kashif Siddique5Combined Military Hospital Tarbela/National University of Medical Sciences (NUMS) Pakistan*Combined Military Hospital Sargodha/ National University of Medical Sciences (NUMS) PakistanCombined Military Hospital Mangla/National University of Medical Sciences (NUMS) PakistanHITEC Institute of Medical Sciences, Taxilla/National University of Medical Sciences (NUMS) PakistanCombined Military Hospital Kharian/National University of Medical Sciences (NUMS) PakistanUniversity of Lahore, Lahore PakistanObjective: To compare World Health Organization treatment for acute watery diarrhea in children with and without probiotic Saccharomyces boulardii in terms of mean duration of diarrhea. Study Design: Comparative cross sectional study. Place and Duration of Study: Combined Military Hospital Tarbela, Pakistan, from Jan 2019 to Jul 2019. Methodology: Eighty four children were enrolled in this study using inclusion and exclusion criteria. Two groups were made. Group A was treated with oral Zinc (10mg for <6 months old, 20mg for >6 months old for 14 days); low osmolarity Oral rehydration salt by 5 ml/kg per hour and continuation of nutritious feeding. Group B was treated with 250mg twice daily Sacchromyces boulardii along with oral Zinc (10mg for <6months old, 20mg for >6 months old for 14 days); low osmolarity Oral rehydration salt by 5 ml/kg per hour and continuation of nutritious feeding. Assessment included anthropometric measurements, hydration status, daily frequency and consistency of stools. Baseline investigations were sent to Combined Military Hospital, Tarbela Laboratory. Data was recorded on a specially designed proforma. Results: Duration of diarrhea was significantly lower in children who were given Saccharomyces boulardii with Zinc as compared to children who were given Zinc alone. i.e., group-A (Zinc): 53.31 hrs vs. group-B (Zinc+ Saccharomyces boulardii): 36.37 hrs, p<0.001 Conclusion: Saccharomyces boulardii can be effectively used with Zinc to treat acute watery diarrhea in children less than five years of age as it significantly reduces mean duration of diarrhea.https://www.pafmj.org/index.php/PAFMJ/article/view/5566/2969childrendiarrheaprobioticsaccharomyces boulardii |
| spellingShingle | Ali Raza Muhammad Zahid Ehsan Qadir Nazir Ahmed Malik Sohail Aslam Kashif Siddique COMPARISON OF WORLD HEALTH ORGANIZATION TREATMENT FOR ACUTE WATERY DIARRHEA IN CHILDREN WITH AND WITHOUT SACCHROMYCES BOULARDII IN TERMS OF MEAN DURATION OF DIARRHEA Pakistan Armed Forces Medical Journal children diarrhea probiotic saccharomyces boulardii |
| title | COMPARISON OF WORLD HEALTH ORGANIZATION TREATMENT FOR ACUTE WATERY DIARRHEA IN CHILDREN WITH AND WITHOUT SACCHROMYCES BOULARDII IN TERMS OF MEAN DURATION OF DIARRHEA |
| title_full | COMPARISON OF WORLD HEALTH ORGANIZATION TREATMENT FOR ACUTE WATERY DIARRHEA IN CHILDREN WITH AND WITHOUT SACCHROMYCES BOULARDII IN TERMS OF MEAN DURATION OF DIARRHEA |
| title_fullStr | COMPARISON OF WORLD HEALTH ORGANIZATION TREATMENT FOR ACUTE WATERY DIARRHEA IN CHILDREN WITH AND WITHOUT SACCHROMYCES BOULARDII IN TERMS OF MEAN DURATION OF DIARRHEA |
| title_full_unstemmed | COMPARISON OF WORLD HEALTH ORGANIZATION TREATMENT FOR ACUTE WATERY DIARRHEA IN CHILDREN WITH AND WITHOUT SACCHROMYCES BOULARDII IN TERMS OF MEAN DURATION OF DIARRHEA |
| title_short | COMPARISON OF WORLD HEALTH ORGANIZATION TREATMENT FOR ACUTE WATERY DIARRHEA IN CHILDREN WITH AND WITHOUT SACCHROMYCES BOULARDII IN TERMS OF MEAN DURATION OF DIARRHEA |
| title_sort | comparison of world health organization treatment for acute watery diarrhea in children with and without sacchromyces boulardii in terms of mean duration of diarrhea |
| topic | children diarrhea probiotic saccharomyces boulardii |
| url | https://www.pafmj.org/index.php/PAFMJ/article/view/5566/2969 |
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